Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | ACHE | P22303 | 5/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | CA9 | Q16790 | 2/20 | 0.35 |
| ▸ | CA5A | P35218 | 1/20 | 0.35 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | RELA | Q04206 | 1/20 | 0.33 |
| ▸ | RORC | P51449 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL43313 | 0.89 | MAPK1 (0.46) | TSHRTDP1MAPK1NPC1MAPT | |
| SCHEMBL18253223 | 0.81 | TSHR (0.50) | TSHRACHETDP1MAPK1NPC1 | |
| SCHEMBL21845090 | 0.81 | TSHR (0.57) | TSHRACHETDP1MAPK1NPC1 | |
| SCHEMBL4188808 | 0.81 | KIF11 (0.41) | MAPK1ALDH1A1ALOX15CYP19A1HSD11B1 | |
| SCHEMBL11152162 | 0.81 | MAPK1 (0.59) | TSHRACHETDP1MAPK1NPC1 | |
| SCHEMBL17885011 | 0.80 | TSHR (0.50) | TSHRACHETDP1NPC1MAPT | |
| SCHEMBL7609864 | 0.79 | TSHR (0.55) | TSHRACHETDP1NPC1MAPT | |
| SCHEMBL9504874 | 0.79 | TSHR (0.62) | TSHRACHETDP1MAPK1NPC1 | |
| SCHEMBL18910984 | 0.78 | CYP2A6 (0.52) | TSHRACHETDP1MAPTALDH1A1 | |
| P-Xylene SCHEMBL19859054 | 0.77 | ACHE (0.53) | TSHRACHETDP1ALDH1A1CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0352672-A2 | Process for the preparation of alkenyl aromatic compounds | BASF Aktiengesellschaft (DE) | 1990-01-31 | — | — | EP | claimed |
| WO-2024134657-A1 | PYRROLOPYRIDINE AND PYRROLOPYRIDAZINE BASED COMPOUNDS AND USE THEREOF AS PKR INHIBITORS | PROTEKT THERAPEUTICS LTD. (IL) | 2024-06-27 | — | — | WO | disclosed |
| EP-3628044-B1 | PYRROLO[2,3-C]PYRIDINES AND RELATED ANALOGS AS LSD-1 INHIBITORS | UNIV MICHIGAN REGENTS (US) | 2023-11-22 | — | — | EP | disclosed |
| US-20230051589-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH NLRP ACTIVITY | NOVARTIS AG (CH) | 2023-02-16 | — | — | US | disclosed |
| WO-2021127337-A1 | TRPML MODULATORS | CASMA THERAPEUTICS, INC. (US) | 2021-06-24 | — | — | WO | disclosed |
| CN-107569645-B | Mongolian medicine for regulating stomach and intestine and its preparing method | 内蒙古民族大学附属医院 | 2021-01-15 | — | — | CN | disclosed |
| US-9778569-B2 | Positive photosensitive resin composition, method for producing film using same, and electronic component | CENTRAL GLASS COMPANY, LIMITED (JP) | 2017-10-03 | — | — | US | disclosed |
| US-20170154766-A1 | SILICON-CONTAINING CONDENSATE, COMPOSITION FOR FORMING A SILICON-CONTAINING RESIST UNDER LAYER FILM, AND PATTERNING PROCESS | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2017-06-01 | — | — | US | disclosed |
| US-20160266491-A1 | Positive Photosensitive Resin Composition, Method for Producing Film Using Same, and Electronic Component | CENTRAL GLASS COMPANY, LIMITED (JP) | 2016-09-15 | — | — | US | disclosed |
| US-20150344473-A1 | TANK-BINDING KINASE INHIBITOR COMPOUNDS | GILEAD SCIENCES, INC. (US) | 2015-12-03 | — | — | US | disclosed |
| EP-0275489-B1 | BENZALDEHYDE DERIVATIVES, THEIR PREPARATION AND APPLICATION | BASF Aktiengesellschaft (DE) | 1989-08-09 | — | — | EP | disclosed |
| US-4847425-A | Prepartion of 4-isopropylcyclohexylmethanol and its alkyl ethers | BASF AKTIENGESELLSCHAFT (DE) | 1989-07-11 | — | — | US | disclosed |
| US-4814510-A | Novel benzaldehyde derivatives, their preparation, and their use | BASF AKTIENGESELLSCHAFT (DE) | 1989-03-21 | — | — | US | disclosed |
| EP-0293739-A1 | Method for the production of 4-isopropyl-cyclohexylmethanol or its alkyl ethers | BASF Aktiengesellschaft (DE) | 1988-12-07 | — | — | EP | disclosed |
| EP-0275489-A1 | Benzaldehyde derivatives, their preparation and application | BASF Aktiengesellschaft (DE) | 1988-07-27 | — | — | EP | disclosed |
| EP-0261962-A2 | Process for producing propylene block copolymer | MITSUBISHI PETROCHEMICAL CO., LTD. (JP) | 1988-03-30 | — | — | EP | disclosed |
| US-4457810-A | ANODIC OXIDATION OF DI-P-TOLYL ETHER IN PRESENCE OF METHANOL | HOECHST AKTIENGESELLSCHAFT (DE) | 1984-07-03 | — | — | US | disclosed |
| EP-0054698-B1 | 4,4'-DIPHENYL ETHER-DIALDEHYDE-BIS-DIMETHYL ACETAL, AND A METHOD FOR ITS PREPARATION | HOECHST AKTIENGESELLSCHAFT (DE) | 1984-06-20 | — | — | EP | disclosed |
| US-4405816-A | INTERMEDIATES FOR POLYETHERS AND LIGHT SEN ITIVE COMPOUNDS | HOECHST AKTIENGESELLSCHAFT (DE) | 1983-09-20 | — | — | US | disclosed |
| EP-0054698-A1 | 4,4'-Diphenyl ether-dialdehyde-bis-dimethyl acetal, and a method for its preparation | HOECHST AKTIENGESELLSCHAFT (DE) | 1982-06-30 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150344473-A1 | TANK-BINDING KINASE INHIBITOR COMPOUNDS | TBKBP1, TNKS1BP1, TNKS | TSHR 2808/4885ACHE 4790/4885TDP1 762/4885 |
| US-20230051589-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH NLRP ACTIVITY | NLRP1, NLRP3, NOD1 | TSHR 4306/4885ACHE 4294/4885TDP1 1361/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.