Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | PKLR | P30613 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 7/20 | 0.38 |
| ▸ | CA1 | P00915 | 6/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | MME | P08473 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | TERT | O14746 | 1/20 | 0.36 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | FYN | P06241 | 1/20 | 0.35 |
| ▸ | MMP2 | P08253 | 1/20 | 0.35 |
| ▸ | MMP9 | P14780 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL421667 | 1.00 | MEN1 (0.39) | MEN1KMT2AGAAALDH1A1LMNA | |
| SCHEMBL2159580 | 1.00 | MEN1 (0.39) | MEN1KMT2AGAAALDH1A1LMNA | |
| SCHEMBL6834106 | 0.83 | PPARG (0.51) | MEN1KMT2APPARGMME | |
| SCHEMBL21359031 | 0.79 | CA2 (0.37) | ALDH1A1PKLRCA2CA1MME | |
| SCHEMBL1627872 | 0.76 | LMNA (0.41) | MEN1KMT2AGAAALDH1A1LMNA | |
| SCHEMBL12984801 | 0.76 | ALDH1A1 (0.49) | MEN1KMT2AALDH1A1LMNAMAPT | |
| SCHEMBL5323263 | 0.76 | LMNA (0.41) | MEN1KMT2AGAAALDH1A1LMNA | |
| SCHEMBL407185 | 0.75 | CA2 (0.50) | ALDH1A1LMNACA2CA1MME | |
| SCHEMBL6672463 | 0.75 | MEN1 (0.55) | MEN1KMT2AGAAALDH1A1MAPT | |
| SCHEMBL407186 | 0.75 | CA2 (0.50) | ALDH1A1LMNACA2CA1MME |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0375554-B1 | PROCESS FOR PRODUCING OPTICALLY ACTIVE THREO-DIHYDROXYPHENYLSERINE DERIVATIVES | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1993-05-05 | — | — | EP | disclosed |
| EP-0375554-A2 | Process for producing optically active threo-dihydroxyphenylserine derivatives | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1990-06-27 | — | — | EP | disclosed |