Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | MMP13 | P45452 | 1/20 | 0.36 |
| ▸ | MME | P08473 | 2/20 | 0.36 |
| ▸ | CASP3 | P42574 | 2/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | CASP7 | P55210 | 1/20 | 0.35 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.35 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.34 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | LTA4H | P09960 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9508989 | 0.88 | MME (0.39) | NPC1RAB9AMMP13MMETAAR1 | |
| SCHEMBL9504934 | 0.83 | ALDH1A1 (0.37) | CASP3NPSR1CASP1CASP7CASP8 | |
| SCHEMBL9508444 | 0.78 | KLK5 (0.53) | KLK5MEN1KMT2A | |
| SCHEMBL29421922 | 0.71 | LMNA (0.46) | MMP13MMENPSR1HPGDALDH1A1 | |
| SCHEMBL10600082 | 0.71 | CPA3 (0.55) | MMP13MMECASP1LTA4H | |
| SCHEMBL10596768 | 0.71 | ABCB1 (0.46) | NPC1RAB9ACTRB1KMT2AALDH1A1 | |
| SCHEMBL9508990 | 0.71 | ATM (0.50) | NPSR1KLK5MEN1KMT2AHPGD | |
| SCHEMBL27866632 | 0.69 | EPHX1 (0.46) | MMP13MME | |
| SCHEMBL18307298 | 0.68 | KMT2A (0.44) | KLK5MEN1KMT2AALDH1A1 | |
| SCHEMBL5577212 | 0.67 | MEN1 (0.50) | RAB9AKLK5MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0556405-A1 | PSEUDOPENTAPEPTIDES WITH IMMUNOMODULATING ACTIVITY | Japan Tobacco Inc. (JP) | 1993-08-25 | — | — | EP | disclosed |
| WO-1993004080-A1 | PSEUDOPENTAPEPTIDES WITH IMMUNOMODULATING ACTIVITY | JAPAN TOBACCO INC. (JP) | 1993-03-04 | — | — | WO | disclosed |