Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMO | O15229 | 10/20 | 0.41 |
| ▸ | DHODH | Q02127 | 4/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | CYP2C8 | P10632 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | FABP4 | P15090 | 2/20 | 0.34 |
| ▸ | FABP5 | Q01469 | 2/20 | 0.34 |
| ▸ | FABP3 | P05413 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9503665 | 0.81 | DHODH (0.55) | KMODHODHCYP2C9CYP3A4CYP2C8 | |
| SCHEMBL8794771 | 0.78 | PTGFR (0.39) | DHODHMEN1KMT2ACYP2C9CYP3A4 | |
| SCHEMBL8794207 | 0.77 | PTGFR (0.45) | DHODHMEN1KMT2ACYP2C9CYP3A4 | |
| SCHEMBL18075851 | 0.75 | PTGFR (0.53) | DHODHMEN1KMT2ACYP2C9FABP4 | |
| SCHEMBL10581093 | 0.71 | DHODH (0.67) | DHODHCYP2C9CYP3A4CYP2C8CYP1A2 | |
| SCHEMBL9502225 | 0.70 | DHODH (0.62) | DHODHCYP2C9CYP3A4CYP2C8CYP1A2 | |
| SCHEMBL10583621 | 0.68 | DHODH (0.57) | DHODHCYP2C9CYP3A4CYP2C8CYP1A2 | |
| SCHEMBL18222148 | 0.68 | TSPO (0.37) | KMOMEN1KMT2ACYP2C9FABP4 | |
| SCHEMBL18222180 | 0.66 | FABP4 (0.58) | DHODHMEN1KMT2ACYP2C9CYP3A4 | |
| SCHEMBL6226362 | 0.65 | AHR (0.52) | KMOMAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0305952-B1 | SUBSTITUTED 2-PHENYL-4-QUINOLINE-CARBOXYLIC ACIDS | AMERICAN CYANAMID COMPANY (US) | 1993-06-02 | — | — | EP | claimed |