Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 6/20 | 0.47 |
| ▸ | RAB9A | P51151 | 6/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | PGR | P06401 | 1/20 | 0.46 |
| ▸ | ELANE | P08246 | 1/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | IDO1 | P14902 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16293318 | 0.82 | ALDH1A1 (0.52) | NPC1RAB9AALDH1A1KMT2AMAPT | |
| SCHEMBL3086433 | 0.82 | LTA4H (0.39) | RAB9AALDH1A1KMT2AMAPTMEN1 | |
| SCHEMBL3071746 | 0.79 | MEN1 (0.44) | ALDH1A1KMT2AMAPTMEN1ALOX15 | |
| SCHEMBL13708756 | 0.79 | SMN1; SMN2 (0.50) | NPC1RAB9AALDH1A1KMT2AMAPT | |
| SCHEMBL13708760 | 0.78 | TUBB4A (0.48) | NPC1RAB9AALDH1A1KMT2AEPHX1 | |
| SCHEMBL3069836 | 0.76 | ALDH1A1 (0.55) | NPC1RAB9AALDH1A1KMT2AMAPT | |
| SCHEMBL6933112 | 0.76 | ALDH1A1 (0.57) | NPC1RAB9AALDH1A1KMT2AMAPT | |
| SCHEMBL12584988 | 0.75 | NPC1 (0.54) | NPC1RAB9AALDH1A1KMT2AMAPT | |
| SCHEMBL11676410 | 0.75 | TDP1 (0.45) | NPC1RAB9AALDH1A1KMT2AMAPT | |
| SCHEMBL76489 | 0.75 | ALDH1A1 (0.67) | NPC1RAB9AALDH1A1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0325336-B1 | OXADIAZOLE COMPOUNDS, THEIR PREPARATION AND THEIR USE AS PESTICIDES | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1993-08-04 | — | — | EP | disclosed |
| US-4929628-A | Oxadiazole compounds, their preparation and their use as pesticides | SHELL INTERNATIONALE RESEARCH MAATSCHAPPIJ, B. V. (NL) | 1990-05-29 | — | — | US | disclosed |
| EP-0325336-A1 | Oxadiazole compounds, their preparation and their use as pesticides | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1989-07-26 | — | — | EP | disclosed |