Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR2 | O95136 | 1/20 | 0.35 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.35 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.35 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.35 |
| ▸ | FDPS | P14324 | 4/20 | 0.34 |
| ▸ | GGPS1 | O95749 | 4/20 | 0.33 |
| ▸ | DNM1 | Q05193 | 3/20 | 0.33 |
| ▸ | SMPD1 | P17405 | 2/20 | 0.33 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.33 |
| ▸ | LAP3 | P28838 | 1/20 | 0.31 |
| ▸ | MMP1 | P03956 | 1/20 | 0.31 |
| ▸ | MMP2 | P08253 | 1/20 | 0.31 |
| ▸ | MMP3 | P08254 | 1/20 | 0.31 |
| ▸ | MMP8 | P22894 | 1/20 | 0.31 |
| ▸ | LPAR3 | Q9UBY5 | 3/20 | 0.30 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11360763 | 0.74 | DNM1 (0.44) | S1PR2S1PR1S1PR3S1PR5FDPS | |
| SCHEMBL3888704 | 0.72 | MMP2 (0.34) | MMP1MMP2MMP3MMP8 | |
| SCHEMBL11356909 | 0.71 | S1PR2 (0.41) | S1PR2S1PR1S1PR3S1PR5FDPS | |
| SCHEMBL9876905 | 0.71 | FDPS (0.36) | S1PR2S1PR1S1PR3S1PR5FDPS | |
| SCHEMBL3889905 | 0.69 | MMP1 (0.41) | S1PR2S1PR1S1PR3S1PR5FDPS | |
| SCHEMBL8134649 | 0.69 | DNM1 (0.48) | S1PR2S1PR1S1PR3S1PR5FDPS | |
| SCHEMBL9504098 | 0.68 | S1PR2 (0.38) | S1PR2S1PR1S1PR3S1PR5FDPS | |
| SCHEMBL10995960 | 0.66 | S1PR2 (0.53) | S1PR2S1PR1S1PR3S1PR5FDPS | |
| SCHEMBL27673962 | 0.66 | DNM1 (0.44) | S1PR2S1PR1S1PR3S1PR5FDPS | |
| SCHEMBL10975325 | 0.65 | TSHR (0.34) | S1PR2S1PR1S1PR3S1PR5FDPS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0370317-B1 | PROCESS FOR THE PREPARATION OF SUBSTITUTED 2-CHLOROPYRIDINES | BAYER AG (DE) | 1993-06-02 | — | — | EP | claimed |
| US-5010201-A | Process for the preparation of substituted 2-chloropyridines | BAYER AKTIENGESELLSCHAFT (DE) | 1991-04-23 | — | — | US | claimed |
| US-5010201-A | Process for the preparation of substituted 2-chloropyridines | BAYER AKTIENGESELLSCHAFT (DE) | 1991-04-23 | — | — | US | disclosed |