Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 8/20 | 0.54 |
| ▸ | THRA | P10827 | 6/20 | 0.44 |
| ▸ | PLK1 | P53350 | 1/20 | 0.43 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.43 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | LPL | P06858 | 1/20 | 0.40 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | CTDSP1 | Q9GZU7 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10957122 | 0.87 | THRB (0.57) | THRBTHRAPLK1ALDH1A1KMT2A | |
| SCHEMBL52038 | 0.87 | ALDH1A1 (0.52) | THRBTHRAPLK1TAS1R3TAS1R1 | |
| SCHEMBL5033447 | 0.81 | THRB (0.47) | THRBTHRATAS1R3TAS1R1ALDH1A1 | |
| SCHEMBL6546970 | 0.79 | KMT2A (0.50) | THRBTHRAPLK1ALDH1A1KMT2A | |
| SCHEMBL6546552 | 0.79 | THRB (0.50) | THRBTHRAPLK1ALDH1A1KMT2A | |
| SCHEMBL29113622 | 0.76 | ACACB (0.44) | THRBALDH1A1LPLLIPG | |
| SCHEMBL12802088 | 0.76 | THRB (0.65) | THRBTHRAPLK1ALDH1A1KMT2A | |
| SCHEMBL10788291 | 0.75 | THRB (0.42) | THRBTHRAPLK1TAS1R3TAS1R1 | |
| SCHEMBL9502648 | 0.75 | ALDH1A1 (0.48) | TAS1R3TAS1R1ALDH1A1KMT2AMEN1 | |
| SCHEMBL9806331 | 0.75 | THRA (0.59) | THRBTHRAPLK1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0279463-B1 | GRAFT POLYMERIZATION OF SUBSTITUTED STYRENE POLYMERS HAVING PENDANT VINYLIDENE GROUPS | Nippon Paint Co., Ltd. (JP) | 1993-05-26 | — | — | EP | disclosed |
| US-4853436-A | Graft polymerization of substituted styrene polymers having pendant vinylidene groups | NIPPON PAINT CO., LTD. (JP) | 1989-08-01 | — | — | US | disclosed |
| EP-0279463-A2 | Graft polymerization of substituted styrene polymers having pendant vinylidene groups | Nippon Paint Co., Ltd. (JP) | 1988-08-24 | — | — | EP | disclosed |