SCHEMBL9505803

SCHEMBL9505803

CCCc1c2ccccc2cc2cccc(Br)c12

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.46
HPGD P15428 2/20 0.46
KDM4E B2RXH2 1/20 0.46
GAA P10253 1/20 0.46
HTR2A P28223 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
CYP1A2 P05177 2/20 0.40
ERBB2 P04626 1/20 0.40
FYN P06241 1/20 0.40
MAOA P21397 1/20 0.40
ACHE P22303 1/20 0.40
AHR P35869 1/20 0.40
GPR84 Q9NQS5 1/20 0.38
CNR2 P34972 4/20 0.37
NCEH1 Q6PIU2 1/20 0.37
CNR1 P21554 2/20 0.35
CES1 P23141 1/20 0.35
HSD17B10 Q99714 1/20 0.34
ATM Q13315 1/20 0.34
MAPT P10636 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7915225 0.84 ALDH1A1 (0.61) ALDH1A1HPGDKDM4EGAAHTR2A
SCHEMBL7939115 0.80 L3MBTL1 (0.44) ALDH1A1HPGDKDM4EHTR2AL3MBTL1
SCHEMBL28375349 0.76 HTR1B (0.44) CNR2NCEH1CNR1
SCHEMBL11302175 0.74 CYP1A2 (0.46) ALDH1A1HPGDKDM4EGAAHTR2A
SCHEMBL27959230 0.73 GAA (0.49) ALDH1A1HPGDKDM4EGAAHTR2A
SCHEMBL30014468 0.73 CYP1A2 (0.48) ALDH1A1HPGDKDM4EHTR2AL3MBTL1
SCHEMBL21313671 0.73 CYP1A2 (0.48) ALDH1A1HPGDKDM4EHTR2AL3MBTL1
SCHEMBL7915017 0.73 HTR2A (0.52) ALDH1A1HPGDKDM4EGAAHTR2A
SCHEMBL2387008 0.73 KDM4E (0.41) ALDH1A1HPGDKDM4EGAAHTR2A
SCHEMBL15303041 0.72 ALDH1A1 (0.47) ALDH1A1HPGDKDM4EGAAHTR2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0369194-B1 SULFONIUM SALTS AND USE AND PREPARATION THEREOF International Business Machines Corporation (US) 1993-07-14 EP disclosed
US-5102772-A Photocurable epoxy composition with sulfonium salt photoinitiator IBM (US) 1992-04-07 US disclosed
US-5047568-A Sulfonium salts and use and preparation thereof INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 1991-09-10 US disclosed
EP-0369194-A2 Sulfonium salts and use and preparation thereof International Business Machines Corporation (US) 1990-05-23 EP disclosed