Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNN4 | O15554 | 1/20 | 0.35 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.34 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.34 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.33 |
| ▸ | SRC | P12931 | 1/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9508170 | 0.78 | KCNN4 (0.43) | KCNN4NR1H2NR1H3CTRB1MAPT | |
| SCHEMBL9173504 | 0.72 | MEN1 (0.35) | KCNN4LMNAALDH1A1MAPTHTT | |
| SCHEMBL10596502 | 0.72 | MEN1 (0.35) | KCNN4LMNAALDH1A1MAPTHTT | |
| SCHEMBL10061323 | 0.68 | PTGER1 (0.37) | LMNAALDH1A1MAPTHTTPOLB | |
| SCHEMBL8652902 | 0.66 | MGLL (0.39) | LMNAMAPTPOLBPTGER1GABRA1 | |
| SCHEMBL9714755 | 0.66 | RIPK1 (0.37) | LMNAALDH1A1POLBPTGER1GABRA1 | |
| SCHEMBL9507537 | 0.65 | MEN1 (0.39) | KCNN4ALDH1A1 | |
| SCHEMBL2372910 | 0.65 | LMNA (0.56) | LMNAALDH1A1MAPTGABRA1GABRB2 | |
| SCHEMBL28261500 | 0.64 | TSHR (0.41) | LMNAALDH1A1MAPTHTTPOLB | |
| SCHEMBL11386037 | 0.64 | LMNA (0.33) | LMNAALDH1A1HTTPOLBPTGER1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0423282-B1 | PROCESS FOR PREPARING N-PHENYL-N-METHOXYACETYL-DL-ALANINE-METHYLESTER DERIVATIVES | NITRO-KEMIA IPARTELEPEK (HU) | 1993-08-04 | — | — | EP | disclosed |
| EP-0423282-A1 | PROCESS FOR PREPARING N-PHENYL-N-METHOXYACETYL-DL-ALANINE-METHYLESTER DERIVATIVES. | NITRO KEMIA IPARTELEPEK (HU) | 1991-04-24 | — | — | EP | disclosed |
| WO-1990012783-A1 | PROCESS FOR PREPARING N-PHENYL-N-METHOXYACETYL-DL-ALANINE-METHYLESTER DERIVATIVES | NITROKÉMIA IPARTELEPEK (HU) | 1990-11-01 | — | — | WO | disclosed |