Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 1/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.50 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | C1R | P00736 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4911297 | 0.81 | TSHR (0.61) | HDAC3HDAC1HDAC2HDAC6RAPGEF4 | |
| SCHEMBL8973265 | 0.81 | TSHR (0.56) | HDAC3HDAC1HDAC2HDAC6RAPGEF4 | |
| SCHEMBL10429444 | 0.80 | TSHR (0.65) | HDAC3HDAC1HDAC2HDAC6MEN1 | |
| SCHEMBL9738354 | 0.79 | RAPGEF4 (0.53) | HDAC3HDAC1HDAC2HDAC6RAPGEF4 | |
| SCHEMBL9506899 | 0.76 | POLB (0.49) | HDAC3HDAC1HDAC2HDAC6MEN1 | |
| SCHEMBL7765087 | 0.74 | HDAC3 (0.56) | HDAC3HDAC1HDAC2HDAC6RAPGEF4 | |
| SCHEMBL10429500 | 0.73 | NPY5R (0.50) | HDAC3HDAC1HDAC2HDAC6RAPGEF4 | |
| SCHEMBL10051472 | 0.72 | KDM4E (0.56) | MEN1KMT2APOLBMAPTCYP2C9 | |
| SCHEMBL10429474 | 0.71 | MAPT (0.54) | HDAC3HDAC1HDAC2HDAC6MEN1 | |
| SCHEMBL10604460 | 0.69 | CXCL8 (0.49) | RAPGEF4MEN1KMT2APOLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0297397-B1 | PREPARATION OF DIAZO AND AZO COMPOUNDS | BAYER AG (DE) | 1993-08-04 | — | — | EP | disclosed |
| US-4942225-A | Preparation of diazo and azo compounds using azidoformamidium salts | BAYER AKTIENGESELLSCHAFT (DE) | 1990-07-17 | — | — | US | disclosed |
| EP-0297397-A2 | Preparation of diazo and azo compounds | BAYER AG (DE) | 1989-01-04 | — | — | EP | disclosed |
| EP-0093306-B1 | METHODS FOR THE PREPARATION OF AZO COMPOUNDS, AND AZO COMPOUNDS | BAYER AG (DE) | 1986-09-24 | — | — | EP | disclosed |
| EP-0093306-A1 | Methods for the preparation of azo compounds, and azo compounds | BAYER AG (DE) | 1983-11-09 | — | — | EP | disclosed |