Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 5/20 | 0.41 |
| ▸ | FGF1 | P05230 | 3/20 | 0.34 |
| ▸ | FGF2 | P09038 | 3/20 | 0.34 |
| ▸ | VEGFA | P15692 | 3/20 | 0.34 |
| ▸ | HPSE | Q9Y251 | 3/20 | 0.34 |
| ▸ | TNF | P01375 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.32 |
| ▸ | PTAFR | P25105 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 2/20 | 0.30 |
| ▸ | GLA | P06280 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.30 |
| ▸ | BLM | P54132 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9506020 | 1.00 | GBA1 (0.41) | GBA1FGF1FGF2VEGFAHPSE | |
| SCHEMBL6574204 | 0.86 | GBA1 (0.46) | GBA1FGF1FGF2VEGFAHPSE | |
| SCHEMBL6574209 | 0.86 | GBA1 (0.46) | GBA1FGF1FGF2VEGFAHPSE | |
| SCHEMBL8992926 | 0.86 | GBA1 (0.46) | GBA1FGF1FGF2VEGFAHPSE | |
| SCHEMBL8660469 | 0.85 | GBA1 (0.42) | GBA1MAPK1PTAFRRECQLGLA | |
| SCHEMBL8992782 | 0.79 | TNF (0.46) | GBA1FGF1FGF2VEGFAHPSE | |
| SCHEMBL8992784 | 0.79 | TNF (0.46) | GBA1FGF1FGF2VEGFAHPSE | |
| SCHEMBL10600403 | 0.76 | GJB2 (0.43) | GBA1FGF1FGF2VEGFAHPSE | |
| SCHEMBL10600399 | 0.76 | GJB2 (0.43) | GBA1FGF1FGF2VEGFAHPSE | |
| SCHEMBL4639776 | 0.76 | GBA1 (0.43) | GBA1FGF1FGF2VEGFAHPSE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0230322-B1 | 2,6-DIDEOXY-2-FLUORO-L-TALOPYRANOSE AND DERIVATES THEREOF AND THE PRODUCTION OF THESE COMPOUNDS | ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JP) | 1993-07-21 | — | — | EP | disclosed |
| US-5034517-A | Process for producing 2,6-dideoxy-2-fluoro-L-talopyranose | ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JP) | 1991-07-23 | — | — | US | disclosed |