Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MGLL | Q99685 | 2/20 | 0.45 |
| ▸ | OXTR | P30559 | 5/20 | 0.42 |
| ▸ | AVPR1A | P37288 | 4/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11020227 | 0.88 | OXTR (0.40) | MEN1KMT2AOXTRAVPR1A | |
| SCHEMBL30854384 | 0.88 | MGLL (0.41) | MEN1KMT2ALMNAMGLL | |
| SCHEMBL22454527 | 0.87 | MEN1 (0.41) | MEN1KMT2AOXTRAVPR1A | |
| SCHEMBL9508809 | 0.86 | MGLL (0.44) | MEN1KMT2ALMNAMGLLOXTR | |
| SCHEMBL9504669 | 0.85 | MGLL (0.38) | MEN1KMT2ALMNAMGLLOXTR | |
| SCHEMBL10677822 | 0.84 | MGLL (0.43) | MEN1KMT2ALMNAMGLLOXTR | |
| SCHEMBL28741494 | 0.83 | MEN1 (0.38) | MEN1KMT2ALMNAMGLLOXTR | |
| SCHEMBL29633776 | 0.81 | MEN1 (0.36) | MEN1KMT2ALMNAMGLLOXTR | |
| SCHEMBL28741471 | 0.81 | TPH1 (0.41) | MEN1KMT2ALMNAOPRM1 | |
| SCHEMBL22454537 | 0.81 | NPC1 (0.41) | MEN1KMT2ALMNAOXTRAVPR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0161939-B1 | ARYLHYDROXAMATES | E.R. Squibb & Sons, Inc. (US) | 1993-07-21 | — | — | EP | disclosed |
| US-4607053-A | L2POXYGENASE INHIBITORS | E. R. SQUIBB & SONS, INC. (US) | 1986-08-19 | — | — | US | disclosed |
| EP-0161939-A2 | Arylhydroxamates | E.R. Squibb & Sons, Inc. (US) | 1985-11-21 | — | — | EP | disclosed |