Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 1/20 | 0.44 |
| ▸ | OXTR | P30559 | 8/20 | 0.44 |
| ▸ | AVPR1A | P37288 | 8/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | AGER | Q15109 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10677822 | 0.89 | MGLL (0.43) | MGLLOXTRAVPR1AMEN1KMT2A | |
| SCHEMBL9506049 | 0.86 | MEN1 (0.46) | MGLLOXTRAVPR1AMEN1KMT2A | |
| SCHEMBL9835089 | 0.84 | ALOX5 (0.47) | MGLLMEN1KMT2ALMNA | |
| SCHEMBL2436091 | 0.78 | MEN1 (0.42) | OXTRAVPR1AMEN1KMT2A | |
| SCHEMBL14897950 | 0.77 | ALDH1A1 (0.38) | OXTRAVPR1AMEN1KMT2AAGER | |
| SCHEMBL9837323 | 0.76 | NPC1 (0.42) | MEN1KMT2A | |
| SCHEMBL5020595 | 0.76 | HDAC1 (0.48) | MGLLMEN1KMT2A | |
| SCHEMBL14876048 | 0.74 | S1PR3 (0.39) | OXTRAVPR1AMEN1KMT2ALMNA | |
| SCHEMBL14875922 | 0.74 | S1PR3 (0.39) | OXTRAVPR1AMEN1KMT2ALMNA | |
| SCHEMBL5440957 | 0.74 | PPARG (0.38) | OXTRAVPR1AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0161939-B1 | ARYLHYDROXAMATES | E.R. Squibb & Sons, Inc. (US) | 1993-07-21 | — | — | EP | disclosed |
| CN-85104470-A | The method for preparing arythydroxamtes | — | 1986-10-01 | — | — | CN | disclosed |
| US-4607053-A | L2POXYGENASE INHIBITORS | E. R. SQUIBB & SONS, INC. (US) | 1986-08-19 | — | — | US | disclosed |
| EP-0161939-A2 | Arylhydroxamates | E.R. Squibb & Sons, Inc. (US) | 1985-11-21 | — | — | EP | disclosed |