Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A5 | Q9Y345 | 2/20 | 0.45 |
| ▸ | CA1 | P00915 | 3/20 | 0.42 |
| ▸ | CA2 | P00918 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | PAOX | Q6QHF9 | 2/20 | 0.39 |
| ▸ | KDM4A | O75164 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.39 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.39 |
| ▸ | CASP2 | P42575 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | GABRR3 | A8MPY1 | 1/20 | 0.38 |
| ▸ | GABRP | O00591 | 1/20 | 0.38 |
| ▸ | GABRD | O14764 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.38 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9508405 | 0.92 | SLC6A5 (0.50) | SLC6A5CA1CA2TSHRPAOX | |
| SCHEMBL9508397 | 0.90 | CASP2 (0.39) | SLC6A5CA1CA2TSHRPAOX | |
| SCHEMBL9505929 | 0.90 | CA1 (0.43) | SLC6A5CA1CA2TSHRPAOX | |
| SCHEMBL24761185 | 0.85 | SLC6A5 (0.51) | SLC6A5CA1CA2TSHRPAOX | |
| SCHEMBL14459970 | 0.83 | SLC6A5 (0.59) | SLC6A5CA1CA2TSHRPAOX | |
| SCHEMBL9506124 | 0.82 | SLC6A5 (0.51) | SLC6A5PAOXKDM4AHIF1ATET2 | |
| SCHEMBL9506141 | 0.82 | CASP2 (0.46) | SLC6A5TSHRPAOXKDM4AHIF1A | |
| SCHEMBL9506089 | 0.81 | MEN1 (0.39) | CA1CA2TSHRPAOXCASP2 | |
| SCHEMBL11142780 | 0.81 | CA1 (0.47) | SLC6A5CA1CA2TSHRPAOX | |
| SCHEMBL6745342 | 0.81 | TSHR (0.54) | SLC6A5CA1CA2TSHRPAOX |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0432000-B1 | REDUCING COMPOSITION FOR PERMANENT HAIRWAVING, COMPRISING AS REDUCING AGENT AN AMINO-MERCAPTOALKYLAMIDE OR ONE OF ITS SALTS, AND ITS USE IN A PROCESS FOR PERMANENT HAIRWAVING | L'OREAL (FR) | 1993-08-11 | — | — | EP | claimed |