Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP2 | P42575 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | SLC6A5 | Q9Y345 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | NAAA | Q02083 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | PAOX | Q6QHF9 | 2/20 | 0.36 |
| ▸ | KDM4A | O75164 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9506141 | 0.92 | CASP2 (0.46) | CASP2TSHRSLC6A5CYP3A4CYP2D6 | |
| SCHEMBL9506058 | 0.90 | SLC6A5 (0.45) | CASP2TSHRSLC6A5LMNACA1 | |
| Alethine SCHEMBL689905 | 0.87 | TSHR (0.41) | CASP2TSHRSLC6A5CYP3A4CYP2D6 | |
| SCHEMBL12829898 | 0.84 | CASP2 (0.46) | CASP2TSHRSLC6A5CYP3A4CYP2D6 | |
| SCHEMBL7204674 | 0.84 | CASP2 (0.52) | CASP2TSHRSLC6A5CYP3A4CYP2D6 | |
| SCHEMBL9506089 | 0.83 | MEN1 (0.39) | CASP2TSHRLMNACA1CA2 | |
| SCHEMBL9508405 | 0.82 | SLC6A5 (0.50) | CASP2TSHRSLC6A5LMNACA1 | |
| SCHEMBL5493471 | 0.82 | SLC6A5 (0.47) | CASP2TSHRSLC6A5CYP3A4CYP2D6 | |
| SCHEMBL7211184 | 0.80 | PAOX (0.56) | CASP2SLC6A5CYP2D6L3MBTL1LMNA | |
| SCHEMBL9505929 | 0.79 | CA1 (0.43) | CASP2TSHRSLC6A5LMNACA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0432000-B1 | REDUCING COMPOSITION FOR PERMANENT HAIRWAVING, COMPRISING AS REDUCING AGENT AN AMINO-MERCAPTOALKYLAMIDE OR ONE OF ITS SALTS, AND ITS USE IN A PROCESS FOR PERMANENT HAIRWAVING | L'OREAL (FR) | 1993-08-11 | — | — | EP | claimed |