Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.54 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.54 |
| ▸ | CLEC4M | Q9H2X3 | 1/20 | 0.51 |
| ▸ | GUSB | P08236 | 13/20 | 0.51 |
| ▸ | MPO | P05164 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9653780 | 0.84 | BRPF1 (0.57) | RAB9AGABRA1GABRB2CLEC4MGUSB | |
| SCHEMBL9506564 | 0.83 | CLEC4M (0.58) | RAB9AGABRA1GABRB2CLEC4MKDM4E | |
| SCHEMBL9650974 | 0.81 | ALDH1A1 (0.71) | RAB9AGABRA1GABRB2CLEC4MKDM4E | |
| SCHEMBL1126279 | 0.81 | CLEC4M (0.78) | RAB9AGABRA1GABRB2CLEC4MGUSB | |
| SCHEMBL2976084 | 0.81 | CSNK2A2 (0.63) | RAB9AGUSBKDM4E | |
| SCHEMBL9272137 | 0.80 | GABRA1 (0.51) | RAB9AGABRA1GABRB2CLEC4MGUSB | |
| SCHEMBL9723928 | 0.80 | CLEC4M (0.64) | RAB9AGABRA1GABRB2CLEC4MKDM4E | |
| Hydrochloric Acid SCHEMBL31157465 | 0.80 | CSNK2A2 (0.61) | RAB9AGUSBKDM4E | |
| Hydrochloric Acid SCHEMBL6206962 | 0.78 | GUSB (0.59) | RAB9AGUSB | |
| SCHEMBL10498633 | 0.77 | GABRA1 (0.86) | GABRA1GABRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0342775-B1 | 4-AMINO-3-ACYLQUINOLINE DERIVATIVES AND THEIR USE AS INHIBITORS OF GASTRIC SECRETION | SMITHKLINE BEECHAM INTERCREDIT B.V. (NL) | 1993-09-15 | — | — | EP | disclosed |
| US-5143920-A | Antiulcer, antisecretory | SMITHKLINE BECKMAN INTERCREDIT B.V. (NL) | 1992-09-01 | — | — | US | disclosed |
| EP-0342775-A1 | 4-Amino-3-acylquinoline derivatives and their use as inhibitors of gastric secretion | SMITHKLINE BEECHAM INTERCREDIT B.V. (NL) | 1989-11-23 | — | — | EP | disclosed |
| WO-1989008105-A1 | 4-AMINO-3-ACYLQUINOLINE DERIVATIVES AND THEIR USE AS INHIBITORS OF GASTRIC SECRETION | SMITHKLINE BECKMAN INTERCREDIT B.V. (NL) | 1989-09-08 | — | — | WO | disclosed |