Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CLEC4M | Q9H2X3 | 1/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.56 |
| ▸ | HPGD | P15428 | 3/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | NR4A2 | P43354 | 3/20 | 0.52 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.51 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | PIM1 | P11309 | 1/20 | 0.46 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.46 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.46 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9506564 | 0.85 | CLEC4M (0.58) | CLEC4MALDH1A1KDM4EHPGDLMNA | |
| SCHEMBL9650974 | 0.83 | ALDH1A1 (0.71) | CLEC4MALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL9653780 | 0.81 | BRPF1 (0.57) | CLEC4MALDH1A1KDM4EHPGDLMNA | |
| SCHEMBL9506409 | 0.80 | RAB9A (0.55) | CLEC4MKDM4EGABRA1GABRB2RAB9A | |
| SCHEMBL9272137 | 0.77 | GABRA1 (0.51) | CLEC4MALDH1A1KDM4EHPGDLMNA | |
| SCHEMBL9652921 | 0.77 | ALDH1A1 (0.65) | CLEC4MALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL9271308 | 0.76 | MAPT (0.61) | CLEC4MALDH1A1KDM4EHPGDLMNA | |
| SCHEMBL9265791 | 0.76 | ALDH1A1 (0.53) | CLEC4MALDH1A1KDM4EHPGDLMNA | |
| SCHEMBL17798752 | 0.75 | NR4A2 (0.68) | CLEC4MALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL14486971 | 0.74 | NR4A2 (0.62) | CLEC4MALDH1A1KDM4EHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5089498-A | Gastrointestinal disorders | SMITHKLINE BECKMAN INTERCREDIT B.V. (NL) | 1992-02-18 | — | — | US | disclosed |
| EP-0339768-A1 | 4-Amino-3-acylquinoline derivatives, and their use as inhibitors of gastric secretion | SMITHKLINE BECKMAN INTERCREDIT B.V. (NL) | 1989-11-02 | — | — | EP | disclosed |