Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9503554 | 0.83 | NPC1 (0.35) | LMNANPC1 | |
| SCHEMBL9506536 | 0.77 | SIGMAR1 (0.48) | — | |
| SCHEMBL9503329 | 0.74 | KDM4E (0.36) | ALDH1A1 | |
| SCHEMBL9504595 | 0.72 | SIGMAR1 (0.36) | ALDH1A1 | |
| Fumaric Acid SCHEMBL9506530 | 0.68 | SIGMAR1 (0.35) | ALDH1A1 | |
| SCHEMBL9503531 | 0.61 | ADRA1D (0.63) | — | |
| Hydrochloric Acid SCHEMBL26688719 | 0.60 | HTR2A (0.47) | ALDH1A1 | |
| SCHEMBL9503551 | 0.59 | SIGMAR1 (0.41) | — | |
| SCHEMBL31321629 | 0.58 | PRSS1 (0.63) | ALDH1A1LMNAMAPTPOLBNPC1 | |
| Oxalic Acid SCHEMBL8728762 | 0.58 | BCHE (0.61) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0321967-B1 | COMPOUNDS ACTIVE ON THE CARDIOVASCULAR SYSTEM | ZAMBON GROUP S.p.A. (IT) | 1993-07-28 | — | — | EP | disclosed |
| EP-0321967-A2 | Compounds active on the cardiovascular system | ZAMBON GROUP S.p.A. (IT) | 1989-06-28 | — | — | EP | disclosed |