Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.53 |
| ▸ | FAAH | O00519 | 1/20 | 0.52 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.52 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.52 |
| ▸ | ELANE | P08246 | 1/20 | 0.52 |
| ▸ | PRTN3 | P24158 | 1/20 | 0.52 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 5/20 | 0.49 |
| ▸ | CA2 | P00918 | 5/20 | 0.49 |
| ▸ | CA9 | Q16790 | 4/20 | 0.49 |
| ▸ | CA12 | O43570 | 3/20 | 0.49 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.49 |
| ▸ | IDO1 | P14902 | 2/20 | 0.48 |
| ▸ | CA7 | P43166 | 2/20 | 0.48 |
| ▸ | CA5A | P35218 | 2/20 | 0.48 |
| ▸ | CA3 | P07451 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28357735 | 0.83 | LOXL2 (0.57) | LOXL2HTTTSHRMEN1KMT2A | |
| SCHEMBL294284 | 0.82 | LOXL2 (0.55) | LOXL2HTTTSHRMEN1KMT2A | |
| SCHEMBL31540565 | 0.81 | TSHR (0.56) | LOXL2TSHRCA1CA2CA9 | |
| Lithium Ion SCHEMBL8022514 | 0.80 | LOXL2 (0.53) | LOXL2HTTTSHRMEN1KMT2A | |
| SCHEMBL515030 | 0.80 | LOXL2 (0.53) | LOXL2HTTTSHRMEN1KMT2A | |
| SCHEMBL1425399 | 0.80 | LOXL2 (0.53) | LOXL2HTTTSHRMEN1KMT2A | |
| SCHEMBL515031 | 0.80 | LOXL2 (0.53) | LOXL2HTTTSHRMEN1KMT2A | |
| SCHEMBL2999944 | 0.80 | CA2 (0.59) | LOXL2HTTTSHRMEN1KMT2A | |
| SCHEMBL1425484 | 0.80 | LOXL2 (0.53) | LOXL2HTTTSHRMEN1KMT2A | |
| SCHEMBL294285 | 0.80 | LOXL2 (0.59) | LOXL2HTTTSHRMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030170811-A1 | Process for the production of alpha-human atrial natriuretic polypeptide | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-09-11 | — | — | US | disclosed |
| US-6403336-B1 | DNA SEGMENT ENCODES PROTECTIVE PEPTIDE-FUSED ATRIOPEPTIN; MICROORGANISMS TRANSFORMED WITH VECTORS; GENETIC ENGINEERING | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-06-11 | — | — | US | disclosed |
| EP-0206769-B2 | A process for the production of alpha-human atrial natriuretic polypeptide | FUJISAWA PHARMACEUTICAL CO (JP) | 1999-11-10 | — | — | EP | disclosed |
| US-5360935-A | From phenylmethanesulfonyl fluorides and phenylacyl bromides, phase transfer agent, base, solvent | NIHON BAYER AGROCHEM K.K. (JP) | 1994-11-01 | — | — | US | disclosed |
| EP-0534249-A2 | Process for the preparation of 3-phenyl-2-propenones | NIHON BAYER AGROCHEM K.K. (JP) | 1993-03-31 | — | — | EP | disclosed |
| EP-0440311-A1 | A process for the production of alpha-human atrial natriuretic polypeptide | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-08-07 | — | — | EP | disclosed |
| EP-0206769-A2 | A process for the production of alpha-human atrial natriuretic polypeptide | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1986-12-30 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030170811-A1 | Process for the production of alpha-human atrial natriuretic polypeptide | NPPA, NPR1, NPR3 | LOXL2 4715/4885FAAH 2511/4885PRSS1 882/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.