Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 13/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 12/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 11/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 11/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 10/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 10/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 10/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 10/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 10/20 | 0.41 |
| ▸ | HDAC9 | Q9UKV0 | 10/20 | 0.41 |
| ▸ | HDAC5 | Q9UQL6 | 10/20 | 0.41 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | NAMPT | P43490 | 1/20 | 0.36 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.36 |
| ▸ | BAZ1A | Q9NRL2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11489249 | 0.82 | LMNA (0.52) | NAMPT | |
| SCHEMBL11067406 | 0.81 | SMN1; SMN2 (0.53) | — | |
| SCHEMBL8761617 | 0.81 | BAZ1A (0.51) | BAZ1A | |
| SCHEMBL9506549 | 0.80 | HDAC3 (0.40) | HDAC1HDAC2HDAC3HDAC6HDAC4 | |
| SCHEMBL9508860 | 0.80 | P2RY12 (0.44) | HDAC1HDAC2HDAC3HDAC6HDAC4 | |
| SCHEMBL9475174 | 0.79 | CNR1 (0.43) | HDAC1HDAC2HDAC3HDAC6HDAC4 | |
| SCHEMBL2704274 | 0.77 | ALDH1A1 (0.50) | — | |
| SCHEMBL9475226 | 0.77 | CNR1 (0.60) | — | |
| SCHEMBL9474666 | 0.77 | CNR1 (0.60) | — | |
| SCHEMBL9474467 | 0.75 | CNR1 (0.64) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0285266-B1 | METAL TREATMENT | ZENECA LIMITED (GB) | 1993-08-25 | — | — | EP | disclosed |
| US-5064723-A | METAL TREATMENT | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-11-12 | — | — | US | disclosed |
| EP-0285266-A2 | Metal treatment | ZENECA LIMITED (GB) | 1988-10-05 | — | — | EP | disclosed |
| EP-0251490-A2 | Metal-polymer adhesion | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1988-01-07 | — | — | EP | disclosed |