Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 3/20 | 0.35 |
| ▸ | TACR1 | P25103 | 2/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | CTSS | P25774 | 5/20 | 0.34 |
| ▸ | CTSL | P07711 | 2/20 | 0.34 |
| ▸ | CTSB | P07858 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | CA7 | P43166 | 2/20 | 0.33 |
| ▸ | CA9 | Q16790 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9506639 | 0.87 | CA1 (0.40) | POLBCA1CTSSCTSLCTSB | |
| SCHEMBL9694637 | 0.79 | TACR1 (0.39) | POLBTACR1CTSSCTSLCTSB | |
| SCHEMBL9504651 | 0.76 | METAP2 (0.43) | POLBCA1TACR1CTSSCTSL | |
| SCHEMBL9506681 | 0.76 | METAP2 (0.43) | POLBCA1TACR1CTSSCTSL | |
| SCHEMBL31074810 | 0.72 | TACR1 (0.45) | CA1TACR1CA2CA7CA9 | |
| SCHEMBL9505567 | 0.71 | POLB (0.38) | POLBCA1TACR1CA2CA7 | |
| SCHEMBL8106389 | 0.71 | CA1 (0.52) | POLBCA1SIGMAR1CA2CA7 | |
| SCHEMBL8838752 | 0.70 | CA1 (0.51) | POLBCA1SIGMAR1CA2CA7 | |
| SCHEMBL23720452 | 0.69 | TSHR (0.44) | CA1TACR1CA2CA7CA9 | |
| SCHEMBL10547943 | 0.69 | CA1 (0.50) | POLBCA1SIGMAR1CA2CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0546115-A1 | PEPTIDES CONTAINING AMINO-POLYOLS AS TRANSITION-STATE MIMICS | THE UPJOHN COMPANY (US) | 1993-06-16 | — | — | EP | disclosed |