Phosphine

Phosphine

SCHEMBL9506700

CC(c1ccccc1)C(Br)(c1ccccc1)c1ccccc1.P

nearest known ligand 0.42

Full drug profile on Sugi Atlas →

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CYP2D6 P10635 3/20 0.41
ALDH1A1 P00352 2/20 0.38
CYP2C19 P33261 1/20 0.38
HSD17B10 Q99714 1/20 0.38
TAAR1 Q96RJ0 3/20 0.38
HTR2A P28223 1/20 0.38
HRH1 P35367 1/20 0.38
AOC3 Q16853 1/20 0.38
RIPK1 Q13546 1/20 0.38
ADRA2A P08913 1/20 0.37
ADRA2C P18825 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
LMNA P02545 1/20 0.37
HIF1A Q16665 1/20 0.37
KDM4E B2RXH2 1/20 0.37
MC4R P32245 1/20 0.36
CYP1A2 P05177 1/20 0.36
KCNN4 O15554 2/20 0.36
MAPK1 P28482 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6050019 0.81 CACNA1F (0.39) CYP2D6ALDH1A1TAAR1HRH1RIPK1
SCHEMBL6741619 0.80 TAAR1 (0.41) CYP2D6ALDH1A1TAAR1RIPK1ADRA2A
SCHEMBL20306752 0.80 RIPK1 (0.45) CYP2D6ALDH1A1TAAR1HRH1AOC3
SCHEMBL27962755 0.79 RIPK1 (0.41) CYP2D6ALDH1A1TAAR1HRH1RIPK1
SCHEMBL18729670 0.77 TAAR1 (0.35) CYP2D6ALDH1A1TAAR1HRH1RIPK1
SCHEMBL5968379 0.77 KIF11 (0.37) CYP2D6ALDH1A1TAAR1HRH1RIPK1
Phosphine SCHEMBL7400153 0.77 CYP2D6 (0.39) CYP2D6ALDH1A1TAAR1AOC3RIPK1
SCHEMBL4151679 0.76 RIPK1 (0.42) CYP2D6ALDH1A1TAAR1HRH1RIPK1
SCHEMBL1538376 0.76 RIPK1 (0.42) CYP2D6ALDH1A1TAAR1HRH1RIPK1
SCHEMBL10634567 0.76 RIPK1 (0.42) CYP2D6ALDH1A1TAAR1HRH1RIPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119978028-A Preparation method of high-temperature-resistant phosphorus salt antistatic agent 达创新材料科技(山东)有限公司 2025-05-13 CN claimed
CN-111205618-A Low-temperature impact-resistant high-transmittance flame-retardant polycarbonate composite material and preparation method thereof 宁波坚锋新材料有限公司 2020-05-29 CN claimed
CN-107759562-B Preparation method of loflupridine hydrochloride 常州四药制药有限公司 2020-10-23 CN disclosed
CN-111205618-A Low-temperature impact-resistant high-transmittance flame-retardant polycarbonate composite material and preparation method thereof 宁波坚锋新材料有限公司 2020-05-29 CN disclosed
EP-0251431-B1 EPOXY RESIN MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1993-07-28 EP disclosed
EP-0251431-A2 Epoxy resin MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1988-01-07 EP disclosed
US-4579582-A REDUCES THE GERMINATION OR EARLY GROWTH OF GRASSES CHEVRON RESEARCH COMPANY (US) 1986-04-01 US disclosed
US-4554010-A 5-Deoxy-3-O-arylmethyl or substituted arylmethyl-1,2-O-substituted-alkylidene-alpha-D-xylofuranose herbicide derivatives CHEVRON RESEARCH COMPANY (US) 1985-11-19 US disclosed
US-4515618-A PLANT GROWTH REGULATORS CHEVRON RESEARCH COMPANY (US) 1985-05-07 US disclosed
US-4429119-A PLANT GROWTH REGULATORS CHEVRON RESEARCH COMPANY (US) 1984-01-31 US disclosed