Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.46 |
| ▸ | MYC | P01106 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.43 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.43 |
| ▸ | DHFR | P00374 | 1/20 | 0.43 |
| ▸ | MPO | P05164 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.43 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL93223 | 0.96 | ESR1 (0.49) | ESR1ESR2MYCALDH1A1HSD17B10 | |
| Hydrochloric Acid SCHEMBL1716527 | 0.94 | ESR1 (0.47) | ESR1ESR2MYCALDH1A1HSD17B10 | |
| SCHEMBL2300929 | 0.84 | ALDH1A1 (0.50) | ESR1ESR2MYCALDH1A1HSD17B10 | |
| SCHEMBL29563004 | 0.83 | MYC (0.52) | MYCALDH1A1HSD17B10KDM4EHPGD | |
| SCHEMBL7067818 | 0.79 | CYP3A4 (0.52) | ESR1MYCALDH1A1HSD17B10KDM4E | |
| SCHEMBL7430270 | 0.79 | MYC (0.49) | MYCALDH1A1HSD17B10KDM4EHPGD | |
| SCHEMBL160022 | 0.78 | ESR1 (0.49) | ESR1ESR2MYCALDH1A1HSD17B10 | |
| SCHEMBL30933674 | 0.78 | ESR1 (0.49) | ESR1ESR2MYCALDH1A1HSD17B10 | |
| SCHEMBL7124951 | 0.78 | TRPA1 (0.48) | ESR1ESR2MYCALDH1A1HSD17B10 | |
| SCHEMBL9864607 | 0.78 | ESR1 (0.52) | ESR1ESR2MYCALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0361645-B1 | ORGANIC HYDRAZINE DERIVATIVES FOR PHARMACEUTICAL USE | ROHM AND HAAS COMPANY (US) | 1993-09-29 | — | — | EP | disclosed |
| EP-0361645-A2 | Organic hydrazine derivatives for pharmaceutical use | ROHM AND HAAS COMPANY (US) | 1990-04-04 | — | — | EP | disclosed |