Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.39 |
| ▸ | TTR | P02766 | 1/20 | 0.39 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.39 |
| ▸ | PGR | P06401 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14637413 | 0.91 | TSHR (0.52) | ALDH1A1ALOX15HPGDKDM4EHSD17B10 | |
| SCHEMBL93223 | 0.88 | ESR1 (0.49) | ALDH1A1ALOX15HPGDKDM4EHSD17B10 | |
| SCHEMBL108670 | 0.86 | ALDH1A1 (0.52) | ALDH1A1ALOX15HPGDKDM4ETSHR | |
| Hydrochloric Acid SCHEMBL1716527 | 0.86 | ESR1 (0.47) | ALDH1A1ALOX15HPGDKDM4EHSD17B10 | |
| SCHEMBL4976492 | 0.86 | TRPA1 (0.48) | ALDH1A1ALOX15HPGDKDM4EHSD17B10 | |
| SCHEMBL19726720 | 0.85 | LMNA (0.50) | ALDH1A1ALOX15KDM4EHSD17B10TSHR | |
| SCHEMBL11080180 | 0.84 | MAPT (0.43) | ALDH1A1ALOX15HPGDKDM4EHSD17B10 | |
| SCHEMBL3710686 | 0.84 | ALDH1A1 (0.42) | ALDH1A1ALOX15HPGDKDM4EHSD17B10 | |
| Hydrazine SCHEMBL9506838 | 0.84 | ESR1 (0.46) | ALDH1A1ALOX15HPGDKDM4EHSD17B10 | |
| SCHEMBL3442002 | 0.84 | ALDH1A1 (0.63) | ALDH1A1ALOX15KMT2AMEN1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112535955-A | Decolorizing membrane and preparation method and application thereof | 中国科学院过程工程研究所 | 2021-03-23 | — | — | CN | claimed |
| EP-0028353-B2 | PROCESS FOR PRODUCING AN AROMATIC POLYESTERPOLYCARBONATE | MITSUBISHI KASEI CORPORATION (JP) | 1987-12-23 | — | — | EP | claimed |
| EP-0010840-B1 | AROMATIC POLYESTER-POLYCARBONATE AND A PROCESS FOR THE PRODUCTION THEREOF | MITSUBISHI KASEI CORPORATION (JP) | 1985-12-04 | — | — | EP | claimed |
| EP-0028353-B1 | PROCESS FOR PRODUCING AN AROMATIC POLYESTERPOLYCARBONATE | MITSUBISHI KASEI CORPORATION (JP) | 1983-09-07 | — | — | EP | claimed |
| US-4369303-A | Process for producing an aromatic polyesterpolycarbonate | MITSUBISHI CHEMICAL INDUSTRIES LIMITED (JP) | 1983-01-18 | — | — | US | claimed |
| EP-0028353-A1 | Process for producing an aromatic polyesterpolycarbonate | MITSUBISHI KASEI CORPORATION (JP) | 1981-05-13 | — | — | EP | claimed |
| US-4260731-A | REACTING A TEREPHTHALOYL OR ISOPHTHALOYL CHLORIDE, AROMATIC DIOL | MITSUBISHI CHEMICAL INDUSTRIES, LTD. (JP) | 1981-04-07 | — | — | US | claimed |
| EP-0010840-A1 | Aromatic polyester-polycarbonate and a process for the production thereof | MITSUBISHI KASEI CORPORATION (JP) | 1980-05-14 | — | — | EP | claimed |
| CN-112535955-B | Decolorizing membrane and preparation method and application thereof | 中国科学院过程工程研究所 | 2022-10-14 | — | — | CN | disclosed |
| CN-112535955-A | Decolorizing membrane and preparation method and application thereof | 中国科学院过程工程研究所 | 2021-03-23 | — | — | CN | disclosed |
| EP-2536276-B1 | NOVEL BEXAROTENE ANALOGS | UNIV ARIZONA (US) | 2016-11-23 | — | — | EP | disclosed |
| US-9174917-B2 | Bexarotene analogs | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) | 2015-11-03 | — | — | US | disclosed |
| EP-2536276-A1 | NOVEL BEXAROTENE ANALOGS | The Arizona Board Of Regents, A Body Corporate Of The State Of Arizona Acting For And On Behalf Of Arizona State University (US) | 2012-12-26 | — | — | EP | disclosed |
| US-20120309833-A1 | NOVEL BEXAROTENE ANALOGS | ARIZONA BOARD OF REGENTS, A BODY CORPORATE OF THE STATE OF ARIZONA ACTING FOR AND ON BEHALF OF ARIZONA STATE UNIVERSITY | 2012-12-06 | — | — | US | disclosed |
| US-4260731-A | REACTING A TEREPHTHALOYL OR ISOPHTHALOYL CHLORIDE, AROMATIC DIOL | MITSUBISHI CHEMICAL INDUSTRIES, LTD. (JP) | 1981-04-07 | — | — | US | disclosed |
| EP-0010840-A1 | Aromatic polyester-polycarbonate and a process for the production thereof | MITSUBISHI KASEI CORPORATION (JP) | 1980-05-14 | — | — | EP | disclosed |
| US-4086215-A | USEFUL IN PRODUCING PURE WATER FROM SALINE WATER | TORAY INDUSTRIES, INC. (JA) | 1978-04-25 | — | — | US | disclosed |
| US-4039502-A | DOPES, SULFURIC ACID, FLUOROSULFONIC ACID | E. I. DU PONT DE NEMOURS & COMPANY (US) | 1977-08-02 | — | — | US | disclosed |
| US-3993625-A | REVERSE OSMOSIS | TORAY INDUSTRIES, INC. (JA) | 1976-11-23 | — | — | US | disclosed |
| US-3966656-A | FIBER AND FILM FORMING | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1976-06-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120309833-A1 | NOVEL BEXAROTENE ANALOGS | TBXA2R, ENPP2, CXCL8 | ALDH1A1 1464/4885ALOX15 43/4885HPGD 156/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.