Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STS | P08842 | 2/20 | 0.50 |
| ▸ | NR1H2 | P55055 | 8/20 | 0.49 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.42 |
| ▸ | MMP2 | P08253 | 2/20 | 0.41 |
| ▸ | MMP1 | P03956 | 1/20 | 0.41 |
| ▸ | MMP3 | P08254 | 1/20 | 0.41 |
| ▸ | MMP7 | P09237 | 1/20 | 0.41 |
| ▸ | MMP13 | P45452 | 1/20 | 0.41 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.41 |
| ▸ | F13A1 | P00488 | 1/20 | 0.40 |
| ▸ | TGM2 | P21980 | 1/20 | 0.40 |
| ▸ | TGM1 | P22735 | 1/20 | 0.40 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.40 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.40 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.40 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.40 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.40 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9006094 | 0.91 | STS (0.49) | STSNR1H2MCL1MMP2MMP1 | |
| SCHEMBL9006196 | 0.84 | STS (0.52) | STSNR1H2MCL1TBXA2RHDAC8 | |
| SCHEMBL12267639 | 0.81 | NR1H2 (0.50) | NR1H2MCL1MMP2NR1H3 | |
| SCHEMBL13106876 | 0.81 | NR1H2 (0.48) | NR1H2MCL1MMP2MMP1MMP3 | |
| SCHEMBL9503295 | 0.81 | NR1H2 (0.48) | NR1H2MCL1MMP2MMP1MMP3 | |
| SCHEMBL9503339 | 0.80 | MMP1 (0.55) | STSNR1H2MMP2MMP1MMP3 | |
| SCHEMBL9506253 | 0.80 | NR1H2 (0.50) | NR1H2MCL1MMP2NR1H3 | |
| SCHEMBL9507059 | 0.80 | NR1H2 (0.50) | NR1H2MCL1MMP2NR1H3 | |
| SCHEMBL9505085 | 0.78 | NR1H2 (0.50) | STSNR1H2MMP2MMP1MMP3 | |
| SCHEMBL30638141 | 0.78 | MMP2 (0.52) | NR1H2MCL1MMP2MMP1MMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0289911-B1 | PYRROLIDINE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-06-16 | — | — | EP | disclosed |
| US-4916152-A | THROMBOXANE A2 ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1990-04-10 | — | — | US | disclosed |
| EP-0289911-A2 | Pyrrolidine derivatives | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1988-11-09 | — | — | EP | disclosed |