SCHEMBL9507099

SCHEMBL9507099

COCCN(CC(C)C)c1cccc(O)c1

nearest known ligand 0.50

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.50
CYP3A4 P08684 1/20 0.50
TSHR P16473 1/20 0.42
OPRM1 P35372 5/20 0.41
OPRD1 P41143 4/20 0.41
OPRK1 P41145 4/20 0.41
PIK3CD O00329 1/20 0.39
CHRNB2 P17787 1/20 0.38
CHRNA4 P43681 1/20 0.38
CRHR1 P34998 3/20 0.36
SLC22A1 O15245 1/20 0.35
HTR7 P34969 3/20 0.34
RET P07949 1/20 0.34
KIF5B P33176 1/20 0.34
KDR P35968 1/20 0.34
LMNA P02545 1/20 0.33
HDAC6 Q9UBN7 1/20 0.33
MTNR1A P48039 1/20 0.33
MTNR1B P49286 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6908896 0.84 ALDH1A1 (0.63) ALDH1A1CYP3A4TSHROPRM1OPRD1
SCHEMBL9322653 0.81 ALDH1A1 (0.56) ALDH1A1CYP3A4TSHROPRM1OPRD1
SCHEMBL9304794 0.80 ALDH1A1 (0.73) ALDH1A1CYP3A4TSHROPRM1OPRD1
SCHEMBL25396055 0.79 ALDH1A1 (0.53) ALDH1A1CYP3A4TSHRCHRNB2CHRNA4
SCHEMBL10020917 0.79 ALDH1A1 (0.53) ALDH1A1CYP3A4TSHRCHRNB2CHRNA4
SCHEMBL30536690 0.79 ALDH1A1 (0.53) ALDH1A1CYP3A4TSHRCHRNB2CHRNA4
SCHEMBL8084726 0.78 ALDH1A1 (0.59) ALDH1A1CYP3A4TSHROPRM1OPRD1
SCHEMBL9543205 0.76 ALDH1A1 (0.53) ALDH1A1CYP3A4TSHRCHRNB2CHRNA4
SCHEMBL28495975 0.76 ALDH1A1 (0.53) ALDH1A1CYP3A4TSHROPRM1OPRD1
SCHEMBL16398249 0.75 ALDH1A1 (0.51) ALDH1A1CYP3A4TSHROPRM1OPRD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-5008546-A None JP disclosed
JP-5004454-A None JP disclosed
JP-4364986-A None JP disclosed
JP-H058546-A THERMAL RECORDING MATERIAL MITSUI TOATSU CHEM INC 1993-01-19 JP disclosed
JP-H054454-A HEAT-SENSITIVE RECORDING MATERIAL MITSUI TOATSU CHEM INC 1993-01-14 JP disclosed
JP-H04364986-A THERMAL RECORDING MATERIAL MITSUI TOATSU CHEM INC 1992-12-17 JP disclosed