Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC25B | P30305 | 1/20 | 0.60 |
| ▸ | ATM | Q13315 | 1/20 | 0.60 |
| ▸ | CES2 | O00748 | 1/20 | 0.56 |
| ▸ | CES1 | P23141 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.51 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.51 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.51 |
| ▸ | KCNJ8 | Q15842 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | TTR | P02766 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10759830 | 0.94 | CES2 (0.62) | CDC25BATMCES2CES1ALDH1A1 | |
| SCHEMBL10613768 | 0.93 | LMNA (0.61) | CDC25BATMCES2CES1ALDH1A1 | |
| SCHEMBL10611174 | 0.91 | LIG1 (0.62) | CDC25BATMCES2CES1ALDH1A1 | |
| SCHEMBL29377967 | 0.88 | CES2 (0.56) | CES2CES1ALDH1A1ALOX15GAA | |
| SCHEMBL896769 | 0.88 | CES2 (0.56) | CES2CES1ALDH1A1ALOX15GAA | |
| SCHEMBL29433447 | 0.87 | AKR1C3 (0.61) | CDC25BATMCES2CES1ALDH1A1 | |
| SCHEMBL333008 | 0.87 | AKR1C3 (0.61) | CDC25BATMCES2CES1ALDH1A1 | |
| SCHEMBL7118447 | 0.86 | SRD5A2 (0.59) | CDC25BATMCES2CES1ALDH1A1 | |
| SCHEMBL29963659 | 0.86 | LIG1 (0.66) | CES2CES1ALDH1A1ALOX15GAA | |
| SCHEMBL398083 | 0.86 | LIG1 (0.66) | CES2CES1ALDH1A1ALOX15GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0298770-B1 | POLY(ARYLENE ETHER KETONES)HAVING BIPHENYLENE-4,4'-DICARBONYL GROUPS | RAYCHEM CORPORATION (US) | 1993-09-29 | — | — | EP | disclosed |
| US-4855387-A | TEREPHTHALOYL OR ISOPHTHALOYL CHLORIDE, DIPHENYL ETHER, P-DIPHENOXYBENZENE, 4,4'-DIPHENOXYBENZOPHENONE | RAYCHEM CORPORATION (US) | 1989-08-08 | — | — | US | disclosed |
| EP-0298770-A2 | Poly(arylene ether ketones)having biphenylene-4,4'-dicarbonyl groups | RAYCHEM CORPORATION (US) | 1989-01-11 | — | — | EP | disclosed |