SCHEMBL896769

SCHEMBL896769

O=C(c1ccc(F)cc1)c1ccccc1F

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES2 O00748 2/20 0.56
CES1 P23141 2/20 0.56
LMNA P02545 4/20 0.55
ALDH1A1 P00352 4/20 0.52
ALOX15 P16050 1/20 0.52
GAA P10253 1/20 0.52
ABCC9 O60706 1/20 0.51
ABCC8 Q09428 1/20 0.51
KCNJ11 Q14654 1/20 0.51
KCNJ8 Q15842 1/20 0.51
HSD11B1 P28845 1/20 0.49
HPGD P15428 4/20 0.49
SMN1; SMN2 Q16637 4/20 0.49
HTT P42858 3/20 0.49
NPSR1 Q6W5P4 2/20 0.49
USP2 O75604 1/20 0.49
ALPG P10696 1/20 0.49
LTA4H P09960 1/20 0.48
MAPT P10636 3/20 0.47
MEN1 O00255 2/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29377967 1.00 CES2 (0.56) CES2CES1LMNAALDH1A1ALOX15
SCHEMBL9409836 0.98 CES2 (0.54) CES2CES1LMNAALDH1A1ALOX15
SCHEMBL2292485 0.94 LMNA (0.57) CES2CES1LMNAALDH1A1ALOX15
SCHEMBL10759830 0.94 CES2 (0.62) CES2CES1LMNAALDH1A1ALOX15
SCHEMBL1754308 0.89 AKR1C3 (0.58) CES2CES1LMNAALDH1A1HPGD
SCHEMBL9507199 0.88 CDC25B (0.60) CES2CES1LMNAALDH1A1ALOX15
Benzene SCHEMBL28318261 0.87 AKR1C3 (0.61) CES2CES1LMNAALDH1A1GAA
SCHEMBL29433447 0.87 AKR1C3 (0.61) CES2CES1LMNAALDH1A1ALOX15
SCHEMBL333008 0.87 AKR1C3 (0.61) CES2CES1LMNAALDH1A1ALOX15
SCHEMBL398083 0.86 LIG1 (0.66) CES2CES1LMNAALDH1A1ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 305 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250215152-A1 POLYARYLETHERKETONE WITH WIDE MOLECULAR WEIGHT DISTRIBUTION AND PREPARATION METHOD THEREFOR JILIN JOINATURE POLYMER CO., LTD. (CN) 2025-07-03 US claimed
EP-4495166-A1 POLYARYLETHERKETONE WITH WIDE MOLECULAR WEIGHT DISTRIBUTION AND PREPARATION METHOD THEREFOR Jilin Joinature Polymer Co., Ltd. (CN) 2025-01-22 EP claimed
US-20240376262-A1 POLYETHERETHERKETONE AND PREPARATION METHOD THEREFOR JILIN JOINATURE POLYMER CO., LTD. (CN) 2024-11-14 US claimed
US-20240360279-A1 HIGH-STRENGTH AND LOW-CHROMA POLYETHERETHERKETONE AND PREPARATION METHOD THEREFOR JILIN JOINATURE POLYMER CO., LTD. (CN) 2024-10-31 US claimed
EP-4386023-A1 POLYETHERETHERKETONE AND PREPARATION METHOD THEREFOR Jilin Joinature Polymer Co., Ltd. (CN) 2024-06-19 EP claimed
EP-4372028-A1 HIGH-STRENGTH AND LOW-CHROMA POLYETHER ETHER KETONE AND PREPARATION METHOD THEREFOR Jilin Joinature Polymer Co., Ltd. (CN) 2024-05-22 EP claimed
CN-113929844-B Polyether-ether-ketone and preparation method thereof 吉林省中研高分子材料股份有限公司 2024-03-08 CN claimed
CN-113563578-B Method for preparing poly (aryl ether ketone) and poly (aryl ether ketone) 吉林省中研高分子材料股份有限公司 2023-12-26 CN claimed
WO-2023202616-A1 POLYARYLETHERKETONE WITH WIDE MOLECULAR WEIGHT DISTRIBUTION AND PREPARATION METHOD THEREFOR 吉林省中研高分子材料股份有限公司 2023-10-26 WO claimed
CN-116891403-A Preparation method of 2,4' -difluorobenzophenone 大连鼎燕医药化工有限公司 2023-10-17 CN claimed
EP-2722353-A1 High purity diphenyl sulfone, preparation and use thereof for the preparation of a poly(aryletherketone) Solvay Specialty Polymers USA, LLC. (US) 2014-04-23 EP claimed
EP-2342259-B1 IMPROVED PROCESS FOR PREPARING A POLY(ARYL ETHER KETONE) USING A HIGH PURITY 4,4'-DIFLUOROBENZOPHENONE SOLVAY SPECIALTY POLYMERS USA (US) 2013-08-07 EP claimed
US-20110213115-A1 Process for preparing a poly(aryl ether ketone) using a high purity 4,4'-difluorobenzophenone SOLVAY ADVANCED POLYMERS, L.L.C. (US) 2011-09-01 US claimed
US-20110201775-A1 High purity diphenyl sulfone, preparation and use thereof for the preparation of a poly(aryletherketone) SOLVAY ADVANCED POLYMERS, L.L.C. (US) 2011-08-18 US claimed
EP-2342260-A1 HIGH PURITY DIPHENYL SULFONE, PREPARATION AND USE THEREOF FOR THE PREPARATION OF A POLY(ARYLETHERKETONE) Solvay Advanced Polymers, L.L.C. (US) 2011-07-13 EP claimed
EP-2342259-A1 IMPROVED PROCESS FOR PREPARING A POLY(ARYL ETHER KETONE) USING A HIGH PURITY 4,4'-DIFLUOROBENZOPHENONE Solvay Advanced Polymers, L.L.C. (US) 2011-07-13 EP claimed
WO-2010046483-A1 IMPROVED PROCESS FOR PREPARING A POLY(ARYL ETHER KETONE) USING A HIGH PURITY 4,4'-DIFLUOROBENZOPHENONE SOLVAY ADVANCED POLYMERS, L.L.C. (US) 2010-04-29 WO claimed
WO-2010046482-A1 HIGH PURITY DIPHENYL SULFONE, PREPARATION AND USE THEREOF FOR THE PREPARATION OF A POLY(ARYLETHERKETONE) SOLVAY ADVANCED POLYMERS, L.L.C. (US) 2010-04-29 WO claimed
EP-0243000-B1 POLYCYANOARYL ETHER, METHOD FOR PREPARING THE SAME AND USES THEREOF IDEMITSU KOSAN COMPANY LIMITED (JP) 1990-10-03 EP claimed
EP-0243000-A1 Polycyanoaryl ether, method for preparing the same and uses thereof IDEMITSU KOSAN COMPANY LIMITED (JP) 1987-10-28 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110201775-A1 High purity diphenyl sulfone, preparation and use thereof for the preparation of a poly(aryletherketone) DHPS, PKM, PCBP1 CES2 4114/4885CES1 3026/4885LMNA 1322/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.