Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.40 |
| ▸ | HPGDS | O60760 | 1/20 | 0.37 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 4/20 | 0.36 |
| ▸ | ADRA1D | P25100 | 3/20 | 0.36 |
| ▸ | LTA4H | P09960 | 1/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.35 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | CASP3 | P42574 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.35 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.35 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.35 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.34 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9510722 | 0.82 | BRD4 (0.43) | BRD4PIN1HPGDSADRA1AADRA1D | |
| SCHEMBL29377827 | 0.82 | BRD4 (0.43) | BRD4PIN1HPGDSADRA1AADRA1D | |
| SCHEMBL3031254 | 0.82 | RAB9A (0.53) | BRD4PIN1HPGDSNOTUMADRA1A | |
| SCHEMBL24097956 | 0.79 | BRD4 (0.41) | BRD4PIN1HPGDSNOTUMADRA1A | |
| SCHEMBL31546532 | 0.79 | NOS3 (0.41) | BRD4PIN1HPGDSADRA1AADRA1D | |
| SCHEMBL8071330 | 0.79 | BRD4 (0.41) | BRD4PIN1HPGDSNOTUMADRA1A | |
| SCHEMBL24388762 | 0.79 | KDM4E (0.38) | BRD4PIN1HPGDSNOTUMADRA1A | |
| SCHEMBL20155994 | 0.77 | CTSA (0.44) | BRD4HPGDSADRA1AADRA1DLTA4H | |
| SCHEMBL30740258 | 0.77 | BRD4 (0.42) | BRD4PIN1HPGDSNOTUMADRA1A | |
| SCHEMBL1290063 | 0.76 | HPGDS (0.42) | BRD4HPGDSLTA4HHCRTR1HCRTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022089406-A1 | NITROGEN-CONTAINING FUSED HETEROCYCLIC COMPOUND, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 上海青煜医药科技有限公司 | 2022-05-05 | — | — | WO | disclosed |
| EP-0297804-B1 | SILVER HALIDE PHOTOGRAPHIC LIGHT-SENSITIVE MATERIAL | KONICA CORPORATION (JP) | 1993-08-18 | — | — | EP | disclosed |
| US-4863846-A | SULFUR | KONICA CORPORATION (JP) | 1989-09-05 | — | — | US | disclosed |
| EP-0297804-A2 | Silver halide photographic light-sensitive material | KONICA CORPORATION (JP) | 1989-01-04 | — | — | EP | disclosed |