Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 3/20 | 0.42 |
| ▸ | APP | P05067 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ABL1 | P00519 | 1/20 | 0.38 |
| ▸ | SRC | P12931 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.37 |
| ▸ | RELA | Q04206 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9507588 | 0.85 | MAOB (0.45) | MAOBAPPALDH1A1MEN1KMT2A | |
| SCHEMBL9509583 | 0.74 | SLC6A4 (0.44) | MEN1KMT2ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL31152928 | 0.73 | APP (0.45) | MAOBAPPALDH1A1MEN1KMT2A | |
| SCHEMBL9508531 | 0.72 | SLC6A4 (0.51) | MAOBAPPALDH1A1SLC6A2SLC6A4 | |
| SCHEMBL9510871 | 0.72 | ALDH1A1 (0.40) | MAOBALDH1A1MEN1KMT2AABL1 | |
| SCHEMBL10687383 | 0.69 | APP (0.58) | MAOBAPPALDH1A1MEN1KMT2A | |
| SCHEMBL12603762 | 0.69 | RAB9A (0.51) | MAOBAPPALDH1A1MEN1KMT2A | |
| SCHEMBL7298052 | 0.69 | POLB (0.65) | MAOBAPPALDH1A1MEN1KMT2A | |
| SCHEMBL22048288 | 0.69 | SLC6A2 (0.46) | ALDH1A1SLC6A2SLC6A4SLC6A3HPGD | |
| SCHEMBL9507220 | 0.68 | GAA (0.44) | MAOBAPPALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0358305-B1 | MERCAPTO-PHENYLALCANOYLAMINO ACID AMIDES, THEIR PREPARATION AND THEIR USE AS COLLAGENASE INHIBITORS | BEECHAM GROUP PLC (GB) | 1993-08-25 | — | — | EP | disclosed |
| US-5124322-A | Antiarthritic agents | BEECHAM GROUP P.L.C. (GB) | 1992-06-23 | — | — | US | disclosed |
| EP-0358305-A1 | Mercapto-phenylalcanoylamino acid amides, their preparation and their use as collagenase inhibitors | BEECHAM GROUP PLC (GB) | 1990-03-14 | — | — | EP | disclosed |