Known targets — ChEMBL curated mechanism
GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BHMGCRMMP1MMP13MMP7MMP8PTGS1PTGS2ileSpolrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.30 |
| ▸ | GMNN | O75496 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | THPO | P40225 | 1/20 | 0.30 |
| ▸ | HBB | P68871 | 1/20 | 0.30 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL2733898 | 0.95 | — | — | |
| SCHEMBL21065818 | 0.95 | MEN1 (0.46) | ALDH1A1TSHRMEN1KMT2AKDM4E | |
| SCHEMBL3369423 | 0.94 | — | — | |
| SCHEMBL9124386 | 0.89 | ALDH1A1 (0.50) | ALDH1A1TSHRMEN1KMT2AKDM4E | |
| Lithium Ion SCHEMBL2231463 | 0.89 | — | — | |
| SCHEMBL301242 | 0.89 | ALDH1A1 (0.50) | ALDH1A1TSHRMEN1KMT2AKDM4E | |
| SCHEMBL5454218 | 0.89 | ALDH1A1 (0.50) | ALDH1A1TSHRMEN1KMT2AKDM4E | |
| Zinc Ion SCHEMBL7212485 | 0.89 | ALDH1A1 (0.50) | ALDH1A1TSHRMEN1KMT2AKDM4E | |
| SCHEMBL1962923 | 0.89 | ALDH1A1 (0.50) | ALDH1A1TSHRMEN1KMT2AKDM4E | |
| SCHEMBL8142677 | 0.89 | ALDH1A1 (0.50) | ALDH1A1TSHRMEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0408418-B1 | METHOD OF HYDROXYLATING PHENOLS AND PHENOL ETHERS | RHONE-POULENC CHIMIE (FR) | 1993-08-25 | — | — | EP | claimed |
| EP-0174684-B1 | SELF-EXTINGUISHING POLYCARBONATE COMPOSITION | ENICHEM TECNORESINE S.p.A. (IT) | 1988-10-19 | — | — | EP | claimed |
| EP-0174684-A1 | Self-extinguishing polycarbonate composition | ENICHEM TECNORESINE S.p.A. (IT) | 1986-03-19 | — | — | EP | claimed |
| CN-114267878-B | Calcium salt electrolyte and electrolyte, and preparation method and application thereof | 深圳先进技术研究院 | 2024-04-12 | — | — | CN | disclosed |
| WO-2023108501-A1 | CALCIUM SALT ELECTROLYTE SOLUTION AND ELECTROLYTE, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | 深圳先进技术研究院 | 2023-06-22 | — | — | WO | disclosed |
| CN-113024214-B | Method for solidifying and stabilizing fly ash by cooperation of phosphogypsum and red mud | 中冶南方都市环保工程技术股份有限公司 | 2022-09-02 | — | — | CN | disclosed |
| CN-113024214-A | Method for solidifying and stabilizing fly ash by cooperation of phosphogypsum and red mud | 中冶南方都市环保工程技术股份有限公司 | 2021-06-25 | — | — | CN | disclosed |
| EP-0174684-B1 | SELF-EXTINGUISHING POLYCARBONATE COMPOSITION | ENICHEM TECNORESINE S.p.A. (IT) | 1988-10-19 | — | — | EP | disclosed |
| US-4663380-A | POTASSIUM FERROCYANIDE OR THIOCYANATE | ENICHEM POLIMERI S.P.A. (IT) | 1987-05-05 | — | — | US | disclosed |
| EP-0174684-A1 | Self-extinguishing polycarbonate composition | ENICHEM TECNORESINE S.p.A. (IT) | 1986-03-19 | — | — | EP | disclosed |