Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CHRNB2 | P17787 | 3/20 | 0.31 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.31 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.31 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.31 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9507495 | 0.82 | HSD17B10 (0.40) | MAPTHSD17B10TSHRACE2 | |
| SCHEMBL10044202 | 0.80 | TSHR (0.38) | ALOX15MAPTHSD17B10TSHRCHRNB2 | |
| SCHEMBL27627896 | 0.80 | ALOX15 (0.39) | ALOX15MAPTHSD17B10TSHRCHRNB2 | |
| SCHEMBL9507791 | 0.79 | ALDH1A1 (0.47) | MAPTTSHRACE2 | |
| SCHEMBL9507272 | 0.78 | ALDH1A1 (0.40) | ALOX15HSD17B10 | |
| SCHEMBL14400108 | 0.78 | ALOX15 (0.40) | ALOX15MAPTCHRNB2CHRNA4CHRNB4 | |
| SCHEMBL9507380 | 0.78 | NAAA (0.46) | MAPTTSHRACE2 | |
| SCHEMBL9507698 | 0.76 | NAAA (0.48) | MAPTTSHRACE2 | |
| SCHEMBL9508048 | 0.76 | NAAA (0.48) | MAPTTSHRACE2 | |
| SCHEMBL9509884 | 0.76 | NAAA (0.48) | MAPTTSHRACE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0388960-B1 | OPTICALLY ACTIVE COMPOUNDS AND THEIR PREPARATION AND USE | HITACHI, LTD. (JP) | 1993-10-06 | — | — | EP | disclosed |
| US-5152919-A | Stability, chemical resistance, high speed response, large spo ntaneous polarization, molecular orientation and wide temperat ure range | HITACHI, LTD. (JP) | 1992-10-06 | — | — | US | disclosed |