SCHEMBL950780

SCHEMBL950780

CSCCc1nccn1C

nearest known ligand 0.41

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
FDPS P14324 1/20 0.41
KMT2A Q03164 3/20 0.40
MEN1 O00255 2/20 0.40
LPO P22079 1/20 0.39
CNR2 P34972 1/20 0.36
TSHR P16473 1/20 0.33
OPRK1 P41145 1/20 0.33
FNTA P49354 1/20 0.33
FNTB P49356 1/20 0.33
TRPM5 Q9NZQ8 1/20 0.33
HTT P42858 1/20 0.33
KDM4E B2RXH2 1/20 0.32
NAMPT P43490 1/20 0.31
DRD4 P21917 1/20 0.30
CHRNB2 P17787 1/20 0.30
CHRNA4 P43681 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27698626 0.98 FDPS (0.40) FDPSKMT2AMEN1LPOCNR2
SCHEMBL950351 0.89 FDPS (0.39) FDPSKMT2AMEN1LPOCNR2
SCHEMBL11445146 0.86 FDPS (0.42) FDPSKMT2AMEN1LPOCNR2
SCHEMBL7154948 0.83 FDPS (0.48) FDPSKMT2AMEN1LPOCNR2
Bromide SCHEMBL29657458 0.81 FDPS (0.47) FDPSKMT2AMEN1LPOCNR2
SCHEMBL952297 0.79
SCHEMBL2398203 0.79 FDPS (0.46) FDPSKMT2AMEN1LPOCNR2
SCHEMBL7166348 0.79 FDPS (0.46) FDPSKMT2AMEN1LPOCNR2
SCHEMBL12580120 0.78 HSP90AA1 (0.32) KMT2ATSHR
SCHEMBL27679741 0.78 FDPS (0.42) FDPSKMT2AMEN1LPOTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7888523-B2 Preparation of platinum(II) complexes PLATCO TECHNOLOGIES (PROPRIETARY) LIMITED (ZA) 2011-02-15 US claimed
US-7589225-B2 Preparation of platinum(II) complexes PLATCO TECHNOLOGIES (PROPRIETARY) LIMITED (ZA) 2009-09-15 US claimed
EP-1789427-B1 PREPARATION OF PLATINUM(II) COMPLEXES PLATCO TECHNOLOGIES PROPRIETAR (ZA) 2009-05-20 EP claimed
US-20080064895-A1 Preparation of Platinum(II) Complexes PLATCO TECHNOLOGIES (PROPRIETARY) LIMITED (ZA) 2008-03-13 US claimed
CN-101018797-A Preparation of platinum (II) complexes PLATCO TECHNOLOGIES PROPRIETAR (ZA) 2007-08-15 CN claimed
EP-1789427-A1 PREPARATION OF PLATINUM(II) COMPLEXES Platco Technologies (Proprietary) Limited (ZA) 2007-05-30 EP claimed
EP-1704156-A1 PLATINUM(II) COMPLEXES, PREPARATION AND USE Platco Technologies (Proprietary) Limited (ZA) 2006-09-27 EP claimed
WO-2006024897-A1 PREPARATION OF PLATINUM(II) COMPLEXES PLATCO TECHNOLOGIES (PROPRIETARY) LIMITED (ZA) 2006-03-09 WO claimed
WO-2005051966-A1 PLATINUM(II) COMPLEXES, PREPARATION AND USE PLATCO TECHNOLOGIES (PROPRIETARY) LIMITED (ZA) 2005-06-09 WO claimed
US-20170049903-A1 COMPLEXING AGENTS FOR COMPOSITIONS CONTAINING INCLUSION COMPLEXES CALIFORNIA INSTITUTE OF TECHNOLOGY 2017-02-23 US disclosed
US-20150031753-A1 COMPLEXING AGENTS FOR COMPOSITIONS CONTAINING INCLUSION COMPLEXES CALANDO PHARMACEUTICALS, INC. (US) 2015-01-29 US disclosed
US-20130197210-A1 COMPLEXING AGENTS FOR COMPOSITIONS CONTAINING INCLUSION COMPLEXES CALANDO PHARMACEUTICALS, INC. (US) 2013-08-01 US disclosed
EP-2011798-B1 Preparation of platinum (II) complexes PLATCO TECHNOLOGIES PROPRIETARY LTD (ZA) 2011-06-29 EP disclosed
EP-2330110-A1 Platinum(II) complexes, preparation and use Platco Technologies (Proprietary) Limited (ZA) 2011-06-08 EP disclosed
WO-2007085957-A1 PREPARATION OF PLATINUM (LL) COMPLEXES PLATCO TECHNOLOGIES (PROPRIETARY) LIMITED (ZA) 2007-08-02 WO disclosed
US-20070167643-A1 Platinum (II) complexes, preparation and use PLATCO TECHNOLOGIES (PROPRIETARY) LIMITED (ZA) 2007-07-19 US disclosed
EP-1789427-A1 PREPARATION OF PLATINUM(II) COMPLEXES Platco Technologies (Proprietary) Limited (ZA) 2007-05-30 EP disclosed
EP-1704156-A1 PLATINUM(II) COMPLEXES, PREPARATION AND USE Platco Technologies (Proprietary) Limited (ZA) 2006-09-27 EP disclosed
WO-2006024897-A1 PREPARATION OF PLATINUM(II) COMPLEXES PLATCO TECHNOLOGIES (PROPRIETARY) LIMITED (ZA) 2006-03-09 WO disclosed
WO-2005051966-A1 PLATINUM(II) COMPLEXES, PREPARATION AND USE PLATCO TECHNOLOGIES (PROPRIETARY) LIMITED (ZA) 2005-06-09 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150031753-A1 COMPLEXING AGENTS FOR COMPOSITIONS CONTAINING INCLUSION COMPLEXES INTS6, EXOSC5, PCBP1 FDPS 318/4885KMT2A 4801/4885MEN1 1142/4885
US-20070167643-A1 Platinum (II) complexes, preparation and use PDCD5, ORC3, PDCD2L FDPS 515/4885KMT2A 3504/4885MEN1 1530/4885
US-20080064895-A1 Preparation of Platinum(II) Complexes SLCO4C1, SLC10A6, OTC FDPS 933/4885KMT2A 2943/4885MEN1 1588/4885
US-20170049903-A1 COMPLEXING AGENTS FOR COMPOSITIONS CONTAINING INCLUSION COMPLEXES INTS6, EXOSC5, PCBP1 FDPS 318/4885KMT2A 4801/4885MEN1 1142/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.