Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 5/20 | 0.50 |
| ▸ | THRB | P10828 | 5/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | ATG4B | Q9Y4P1 | 11/20 | 0.48 |
| ▸ | PLA2G1B | P04054 | 9/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9504824 | 0.85 | THRA (0.50) | THRATHRBMEN1KMT2A | |
| SCHEMBL9508886 | 0.78 | THRA (0.52) | THRATHRBMEN1KMT2A | |
| SCHEMBL27671415 | 0.77 | THRA (0.49) | THRATHRBMEN1KMT2A | |
| SCHEMBL9506911 | 0.77 | THRA (0.57) | THRATHRBMEN1KMT2A | |
| SCHEMBL11115180 | 0.74 | TSHR (0.49) | MEN1KMT2A | |
| SCHEMBL9506661 | 0.74 | HDAC1 (0.48) | THRATHRBMEN1KMT2A | |
| SCHEMBL9506028 | 0.73 | THRA (0.52) | THRATHRBMEN1KMT2AATG4B | |
| Phenol SCHEMBL28100119 | 0.73 | THRB (0.57) | THRATHRBMEN1KMT2AATG4B | |
| SCHEMBL9508884 | 0.72 | THRA (0.51) | THRATHRBMEN1KMT2AATG4B | |
| SCHEMBL9508914 | 0.72 | THRA (0.56) | THRATHRBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0161939-B1 | ARYLHYDROXAMATES | E.R. Squibb & Sons, Inc. (US) | 1993-07-21 | — | — | EP | disclosed |
| US-4607053-A | L2POXYGENASE INHIBITORS | E. R. SQUIBB & SONS, INC. (US) | 1986-08-19 | — | — | US | disclosed |
| EP-0161939-A2 | Arylhydroxamates | E.R. Squibb & Sons, Inc. (US) | 1985-11-21 | — | — | EP | disclosed |