Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 2/20 | 0.58 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.56 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | PPARG | P37231 | 1/20 | 0.53 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.51 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.51 |
| ▸ | LTB4R | Q15722 | 2/20 | 0.50 |
| ▸ | LTB4R2 | Q9NPC1 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10412775 | 0.86 | PKM (0.64) | MEN1KMT2ANPC1RAB9A | |
| SCHEMBL9506078 | 0.85 | ALOX5 (0.63) | ALOX5MEN1KMT2A | |
| SCHEMBL9877598 | 0.84 | ALOX5 (0.68) | ALOX5 | |
| SCHEMBL6952535 | 0.82 | L3MBTL1 (0.69) | FFAR1PLA2G4BMEN1KMT2ANPC1 | |
| SCHEMBL27613074 | 0.82 | FFAR1 (0.69) | FFAR1PLA2G4BMEN1KMT2ANPC1 | |
| SCHEMBL4361279 | 0.82 | PLA2G4B (0.76) | FFAR1PLA2G4BMEN1KMT2ANPC1 | |
| SCHEMBL5049112 | 0.80 | PPARG (0.71) | FFAR1PLA2G4BMEN1KMT2ANPC1 | |
| SCHEMBL4364300 | 0.79 | MAPT (0.74) | FFAR1PLA2G4BMEN1KMT2ANPC1 | |
| SCHEMBL10682331 | 0.79 | PARP10 (0.73) | FFAR1PLA2G4BMEN1KMT2ANPC1 | |
| SCHEMBL9042056 | 0.79 | FFAR1 (0.65) | FFAR1PLA2G4BMEN1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0161939-B1 | ARYLHYDROXAMATES | E.R. Squibb & Sons, Inc. (US) | 1993-07-21 | — | — | EP | claimed |
| US-4607053-A | L2POXYGENASE INHIBITORS | E. R. SQUIBB & SONS, INC. (US) | 1986-08-19 | — | — | US | claimed |
| EP-0161939-A2 | Arylhydroxamates | E.R. Squibb & Sons, Inc. (US) | 1985-11-21 | — | — | EP | claimed |
| EP-0161939-B1 | ARYLHYDROXAMATES | E.R. Squibb & Sons, Inc. (US) | 1993-07-21 | — | — | EP | disclosed |
| CN-1012500-B | Process for preparing aryl hydroxamates | SQUIBB & SONS INC (US) | 1991-05-01 | — | — | CN | disclosed |
| CN-85104470-A | The method for preparing arythydroxamtes | — | 1986-10-01 | — | — | CN | disclosed |
| US-4607053-A | L2POXYGENASE INHIBITORS | E. R. SQUIBB & SONS, INC. (US) | 1986-08-19 | — | — | US | disclosed |
| EP-0161939-A2 | Arylhydroxamates | E.R. Squibb & Sons, Inc. (US) | 1985-11-21 | — | — | EP | disclosed |