Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.43 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.37 |
| ▸ | DRD1 | P21728 | 1/20 | 0.36 |
| ▸ | DRD4 | P21917 | 2/20 | 0.36 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.36 |
| ▸ | CACNA1G | O43497 | 4/20 | 0.36 |
| ▸ | CACNA1H | O95180 | 4/20 | 0.36 |
| ▸ | CACNA1I | Q9P0X4 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | ACE | P12821 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9509175 | 0.84 | NOTUM (0.40) | NOTUMALDH1A1GAAHTTPOLB | |
| SCHEMBL9508465 | 0.84 | NOTUM (0.40) | NOTUMOPRD1DRD4ABHD6ALDH1A1 | |
| SCHEMBL9511217 | 0.82 | OPRD1 (0.42) | NOTUMOPRD1DRD1DRD4ABHD6 | |
| SCHEMBL9509051 | 0.78 | SMN1; SMN2 (0.43) | NOTUMOPRD1DRD1CACNA1GCACNA1H | |
| SCHEMBL2138396 | 0.76 | DRD1 (0.59) | DRD1ACE | |
| SCHEMBL9508450 | 0.74 | HHAT (0.40) | NOTUMALDH1A1HTT | |
| SCHEMBL10481211 | 0.67 | PRCP (0.44) | NOTUMOPRD1DRD1DRD4CACNA1G | |
| SCHEMBL8025229 | 0.66 | NOTUM (0.42) | NOTUMDRD4DRD2 | |
| SCHEMBL8011443 | 0.66 | NOTUM (0.42) | NOTUMDRD4DRD2 | |
| SCHEMBL8025232 | 0.66 | NOTUM (0.42) | NOTUMDRD4DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0230871-B1 | HALOACYL 1-SUBSTITUTED-1,2,3,4-TETRAHYDROISOQUINOLINES AS HERBICIDE ANTIDOTES | Monsanto Company (US) | 1993-09-22 | — | — | EP | claimed |
| EP-0230871-A2 | Haloacyl 1-substituted-1,2,3,4-tetrahydroisoquinolines as herbicide antidotes | Monsanto Company (US) | 1987-08-05 | — | — | EP | claimed |
| EP-0230871-B1 | HALOACYL 1-SUBSTITUTED-1,2,3,4-TETRAHYDROISOQUINOLINES AS HERBICIDE ANTIDOTES | Monsanto Company (US) | 1993-09-22 | — | — | EP | disclosed |
| US-4755218-A | Reducing acetochlor injury to corn by applying with antidote | MONSANTO COMPANY (US) | 1988-07-05 | — | — | US | disclosed |
| EP-0230871-A2 | Haloacyl 1-substituted-1,2,3,4-tetrahydroisoquinolines as herbicide antidotes | Monsanto Company (US) | 1987-08-05 | — | — | EP | disclosed |