Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | F2 | P00734 | 2/20 | 0.47 |
| ▸ | MAOA | P21397 | 2/20 | 0.47 |
| ▸ | MAOB | P27338 | 2/20 | 0.47 |
| ▸ | PLG | P00747 | 1/20 | 0.46 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.46 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.46 |
| ▸ | C1S | P09871 | 1/20 | 0.46 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.46 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.43 |
| ▸ | CES2 | O00748 | 2/20 | 0.42 |
| ▸ | CES1 | P23141 | 2/20 | 0.42 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.41 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL154429 | 0.83 | KDM4E (0.55) | ALDH1A1MAOAMAOBMAPK8CES2 | |
| SCHEMBL28638604 | 0.83 | PIK3CA (0.55) | ALDH1A1CYP1A2CYP3A4CYP2C19F2 | |
| SCHEMBL6864288 | 0.81 | CES2 (0.46) | ALDH1A1MAOAMAOBMAPK8SIGMAR1 | |
| SCHEMBL8691992 | 0.81 | MAOA (0.51) | ALDH1A1MAOAMAOBMAPK8SIGMAR1 | |
| SCHEMBL7638353 | 0.78 | MAOA (0.44) | MAOAMAOBMAPK8SIGMAR1RIPK1 | |
| SCHEMBL1699590 | 0.78 | MAOA (0.50) | ALDH1A1MAOAMAOBMAPK8SIGMAR1 | |
| SCHEMBL29718749 | 0.78 | CA2 (0.52) | ALDH1A1MAOAMAOBMAPK8CES2 | |
| SCHEMBL2173469 | 0.78 | MAPK8 (0.44) | ALDH1A1MAOAMAOBMAPK8SIGMAR1 | |
| SCHEMBL1115081 | 0.78 | CA2 (0.52) | ALDH1A1MAOAMAOBMAPK8CES2 | |
| SCHEMBL4685450 | 0.78 | MAPK8 (0.44) | ALDH1A1MAOAMAOBMAPK8SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0206460-B1 | L-PHENYLALANINE DEHYDROGENASE AND USE THEREOF | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1993-08-11 | — | — | EP | disclosed |
| EP-0513872-A1 | L-phenylalanine dehydrogenase and use thereof | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1992-11-19 | — | — | EP | disclosed |
| US-4849345-A | L-phenylalanine dehydrogenase and use thereof | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1989-07-18 | — | — | US | disclosed |
| EP-0206460-A2 | L-phenylalanine dehydrogenase and use thereof | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1986-12-30 | — | — | EP | disclosed |