Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHA2 | P29317 | 2/20 | 0.41 |
| ▸ | XIAP | P98170 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 8/20 | 0.39 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.38 |
| ▸ | GRB2 | P62993 | 1/20 | 0.38 |
| ▸ | NTSR2 | O95665 | 1/20 | 0.38 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.38 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.38 |
| ▸ | NRP1 | O14786 | 1/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 6/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7785522 | 0.85 | OPRM1 (0.43) | EPHA2XIAPOPRM1CXCR4NTSR2 | |
| SCHEMBL9614905 | 0.84 | OPRM1 (0.38) | EPHA2XIAPOPRM1CXCR4NTSR2 | |
| SCHEMBL8969918 | 0.84 | EPHA2 (0.49) | EPHA2XIAPOPRM1CXCR4GRB2 | |
| SCHEMBL7788531 | 0.84 | CXCR4 (0.45) | EPHA2XIAPOPRM1CXCR4NTSR2 | |
| SCHEMBL10378224 | 0.84 | EPHA2 (0.48) | EPHA2XIAPNTSR2NTSR1SORT1 | |
| SCHEMBL10378950 | 0.84 | EPHA2 (0.48) | EPHA2XIAPOPRM1CXCR4NTSR2 | |
| SCHEMBL31303183 | 0.82 | NRP1 (0.52) | EPHA2XIAPOPRM1CXCR4GRB2 | |
| SCHEMBL7785535 | 0.82 | NTSR2 (0.42) | EPHA2OPRM1GRB2NTSR2NTSR1 | |
| SCHEMBL8970642 | 0.82 | EPHA2 (0.47) | EPHA2XIAPNTSR2NTSR1SORT1 | |
| SCHEMBL31487190 | 0.81 | NRP1 (0.47) | XIAPOPRM1GRB2NTSR2NTSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0556405-A1 | PSEUDOPENTAPEPTIDES WITH IMMUNOMODULATING ACTIVITY | Japan Tobacco Inc. (JP) | 1993-08-25 | — | — | EP | disclosed |