Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCI | P41743 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | BIRC5 | O15392 | 1/20 | 0.36 |
| ▸ | F2 | P00734 | 2/20 | 0.35 |
| ▸ | F10 | P00742 | 2/20 | 0.35 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.35 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | CDC7 | O00311 | 2/20 | 0.35 |
| ▸ | CDK2 | P24941 | 2/20 | 0.35 |
| ▸ | ACHE | P22303 | 2/20 | 0.34 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9506012 | 0.86 | MAPT (0.34) | F2ALOX15MAPT | |
| SCHEMBL257517 | 0.79 | PRKCI (0.55) | PRKCIKCNH2BIRC5ALDH1A1ALOX15 | |
| SCHEMBL29755944 | 0.77 | PRKCI (0.57) | PRKCIKCNH2BIRC5ALDH1A1ALOX15 | |
| SCHEMBL9508601 | 0.76 | SRC (0.42) | GPR35ALDH1A1HTTCDC7SRC | |
| SCHEMBL1664307 | 0.72 | ROCK2 (0.50) | KCNH2ALDH1A1HTTPLA2G4AHDAC3 | |
| SCHEMBL6990859 | 0.72 | BIRC5 (0.67) | PRKCIBIRC5ALDH1A1ALOX15CDC7 | |
| SCHEMBL27693088 | 0.71 | ALDH1A1 (0.39) | ALDH1A1ALOX15HTTATMSMN1; SMN2 | |
| SCHEMBL4572982 | 0.70 | KCNH2 (0.60) | PRKCIKCNH2BIRC5ALDH1A1ALOX15 | |
| SCHEMBL16862053 | 0.70 | BIRC5 (0.59) | PRKCIKCNH2BIRC5ALDH1A1ALOX15 | |
| SCHEMBL30364829 | 0.70 | KCNH2 (0.60) | PRKCIKCNH2BIRC5ALDH1A1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0335477-B1 | THE USE OF N-SUBSTITUTED-5,6-DIHYDROXYINDOLES AS A HAIR COLORING AGENT | Bristol-Myers Squibb Company (US) | 1993-07-21 | — | — | EP | claimed |
| EP-0335477-A2 | The use of N-substituted-5,6-dihydroxyindoles as a hair coloring agent | Bristol-Myers Squibb Company (US) | 1989-10-04 | — | — | EP | claimed |