SCHEMBL9508653

SCHEMBL9508653

Cc1cc(N(C)C)ccc1C=C1CCC(=Cc2ccc(N(C)C)cc2C)C1=O

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE P22303 5/20 0.58
PTGS2 P35354 6/20 0.53
BCHE P06276 2/20 0.53
CYP1A2 P05177 1/20 0.51
KMT2A Q03164 4/20 0.49
MAPT P10636 4/20 0.49
MEN1 O00255 3/20 0.49
LMNA P02545 2/20 0.49
NPC1 O15118 1/20 0.49
MAPK1 P28482 1/20 0.49
RAB9A P51151 1/20 0.49
SMN1; SMN2 Q16637 1/20 0.49
MCOLN3 Q8TDD5 1/20 0.49
L3MBTL1 Q9Y468 1/20 0.49
ALDH1A1 P00352 3/20 0.47
GAA P10253 1/20 0.44
EGFR P00533 1/20 0.44
CYP26A1 O43174 1/20 0.43
MIF P14174 1/20 0.43
CYP2C9 P11712 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9506413 0.94 ACHE (0.67) ACHEPTGS2BCHECYP1A2KMT2A
SCHEMBL29264644 0.85 PTGS2 (0.71) ACHEPTGS2KMT2AMAPTMEN1
SCHEMBL1416418 0.83 S100B (0.45) ACHEPTGS2BCHECYP1A2KMT2A
SCHEMBL1416417 0.83 S100B (0.45) ACHEPTGS2BCHECYP1A2KMT2A
SCHEMBL9342036 0.78 ACHE (0.49) ACHECYP1A2KMT2AMAPTMEN1
SCHEMBL11319345 0.78 ACHE (0.49) ACHECYP1A2KMT2AMAPTMEN1
SCHEMBL9168847 0.78 PTGS2 (0.69) ACHEPTGS2BCHEKMT2AMAPT
SCHEMBL29286007 0.77 ACHE (0.65) ACHEPTGS2BCHECYP1A2KMT2A
SCHEMBL2868624 0.74 CYP1A2 (0.86) CYP1A2KMT2AMAPTMEN1LMNA
SCHEMBL11966165 0.74 CYP1A2 (0.86) CYP1A2KMT2AMAPTMEN1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0364120-B1 A CYCLOALKENE COMPOUND AND A RECORDING MATERIAL USING THE COMPOUND HODOGAYA CHEMICAL COMPANY, LIMITED (JP) 1993-08-11 EP disclosed
US-4987262-A Absorbers of near infrared radiation, chromogens HODOGAYA CHEMICAL CO., LTD. (JP) 1991-01-22 US disclosed
EP-0364120-A2 A cycloalkene compound and a recording material using the compound HODOGAYA CHEMICAL COMPANY, LIMITED (JP) 1990-04-18 EP disclosed