Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 8/20 | 0.37 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.34 |
| ▸ | ACACB | O00763 | 3/20 | 0.33 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | GRM5 | P41594 | 1/20 | 0.33 |
| ▸ | RARA | P10276 | 1/20 | 0.32 |
| ▸ | RARB | P10826 | 1/20 | 0.32 |
| ▸ | RARG | P13631 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9509130 | 1.00 | FFAR1 (0.37) | FFAR1CYP2A6KCNH2ACACBKDM1A | |
| SCHEMBL9511355 | 0.94 | CYP2A6 (0.39) | FFAR1CYP2A6ACACBRARARARB | |
| SCHEMBL9508754 | 0.90 | LMNA (0.40) | FFAR1CYP2A6ACACBGRM5RARA | |
| SCHEMBL9510036 | 0.89 | GRM5 (0.39) | FFAR1CYP2A6KCNH2CA12CA2 | |
| SCHEMBL9512412 | 0.89 | FFAR1 (0.41) | FFAR1ACACB | |
| SCHEMBL9512352 | 0.89 | FFAR1 (0.41) | FFAR1ACACB | |
| SCHEMBL9512399 | 0.87 | FFAR1 (0.36) | FFAR1CYP2A6ACACBKDM1ARARB | |
| SCHEMBL9509318 | 0.87 | FFAR1 (0.36) | FFAR1CYP2A6ACACBKDM1ARARB | |
| SCHEMBL10511143 | 0.87 | TSHR (0.40) | FFAR1RARARARBRARG | |
| SCHEMBL10512751 | 0.87 | TSHR (0.40) | FFAR1RARARARBRARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0308438-B1 | LIQUID CRYSTAL PHASE CONTAINING TOLANES | MERCK PATENT GmbH (DE) | 1993-09-29 | — | — | EP | disclosed |