Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9510282 | 0.80 | ALDH1A1 (0.38) | ALDH1A1KDM4EGAACYP2C9HPGD | |
| SCHEMBL7941934 | 0.73 | SMN1; SMN2 (0.47) | ALDH1A1GAASMN1; SMN2MAPTKMT2A | |
| SCHEMBL15310434 | 0.68 | MEN1 (0.31) | ALDH1A1KMT2AMEN1 | |
| SCHEMBL23706559 | 0.65 | SMN1; SMN2 (0.36) | ALDH1A1KDM4EGAACYP2C9HPGD | |
| SCHEMBL8429253 | 0.63 | SMN1; SMN2 (0.34) | ALDH1A1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL8429251 | 0.63 | SMN1; SMN2 (0.34) | ALDH1A1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL167473 | 0.63 | SMN1; SMN2 (0.34) | ALDH1A1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL4466648 | 0.61 | CHRNB2 (0.53) | ALDH1A1KDM4EHPGDCYP2C19SMN1; SMN2 | |
| SCHEMBL1911517 | 0.61 | CHRNB2 (0.53) | ALDH1A1KDM4EHPGDCYP2C19SMN1; SMN2 | |
| SCHEMBL30492736 | 0.61 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0298680-B1 | HERBICIDAL COMPOSITIONS OF ACYLATED 1,3-DICARBONYL HERBICIDES AND ANTIDOTES THEREFOR | ZENECA INC. (US) | 1993-09-15 | — | — | EP | disclosed |
| EP-0298680-A2 | Herbicidal compositions of acylated 1,3-dicarbonyl herbicides and antidotes therefor | ZENECA INC. (US) | 1989-01-11 | — | — | EP | disclosed |