Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9508760 | 0.80 | ALDH1A1 (0.37) | ALDH1A1KDM4EGAACYP2C9HPGD | |
| Zinc Ion SCHEMBL11709710 | 0.72 | PDK1 (0.34) | — | |
| SCHEMBL7941934 | 0.69 | SMN1; SMN2 (0.47) | ALDH1A1GAASMN1; SMN2MAPT | |
| SCHEMBL11481879 | 0.68 | ALDH1A1 (0.30) | ALDH1A1MAPT | |
| SCHEMBL11482743 | 0.63 | ALDH1A1 (0.31) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL167473 | 0.63 | SMN1; SMN2 (0.34) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL8429251 | 0.63 | SMN1; SMN2 (0.34) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL8429253 | 0.63 | SMN1; SMN2 (0.34) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL1911517 | 0.62 | CHRNB2 (0.53) | ALDH1A1KDM4EHPGDCYP2C19SMN1; SMN2 | |
| SCHEMBL4466648 | 0.62 | CHRNB2 (0.53) | ALDH1A1KDM4EHPGDCYP2C19SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4197110-A | HALOMETHYL-3-ACETYL OXAZINE OR OXAZOLIDINE | PRODUITS CHIMIQUES UGINE KUHLMANN (FR) | 1980-04-08 | — | — | US | claimed |
| EP-0298680-B1 | HERBICIDAL COMPOSITIONS OF ACYLATED 1,3-DICARBONYL HERBICIDES AND ANTIDOTES THEREFOR | ZENECA INC. (US) | 1993-09-15 | — | — | EP | disclosed |
| EP-0298680-A2 | Herbicidal compositions of acylated 1,3-dicarbonyl herbicides and antidotes therefor | ZENECA INC. (US) | 1989-01-11 | — | — | EP | disclosed |
| US-4197110-A | HALOMETHYL-3-ACETYL OXAZINE OR OXAZOLIDINE | PRODUITS CHIMIQUES UGINE KUHLMANN (FR) | 1980-04-08 | — | — | US | disclosed |