SCHEMBL9508781

SCHEMBL9508781

C=CCC(=O)C(C)c1ccccc1

nearest known ligand 0.49

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CYP2C19 P33261 1/20 0.49
PTGS2 P35354 3/20 0.43
FAAH O00519 1/20 0.39
APAF1 O14727 1/20 0.39
GRM7 Q14831 2/20 0.38
BCHE P06276 1/20 0.38
HTR1A P08908 1/20 0.38
ADRB3 P13945 1/20 0.38
HTR2A P28223 1/20 0.38
HTR2C P28335 1/20 0.38
DRD3 P35462 1/20 0.38
HTR2B P41595 1/20 0.38
HTR6 P50406 1/20 0.38
POLB P06746 1/20 0.38
HPGD P15428 1/20 0.38
ERCC1 P07992 1/20 0.38
ERCC4 Q92889 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4588469 0.79 PTGS2 (0.47) PTGS2FAAHAPAF1GRM7BCHE
SCHEMBL508956 0.78 PTGS2 (0.50) PTGS2FAAHAPAF1GRM7POLB
SCHEMBL27817116 0.78 PTGS2 (0.56) CYP2C19PTGS2APAF1ADRB3HTR2A
SCHEMBL10728103 0.76 PTGS2 (0.48) PTGS2FAAHAPAF1
SCHEMBL13389325 0.76 ALDH1A1 (0.50) PTGS2FAAHGRM7
SCHEMBL3410010 0.76 ALDH1A1 (0.50) PTGS2FAAHGRM7
SCHEMBL10676559 0.75 CYP3A4 (0.51) CYP2C19PTGS2
SCHEMBL14587548 0.75 CYP3A4 (0.51) CYP2C19PTGS2
SCHEMBL4436336 0.75 FAAH (0.62) PTGS2FAAHAPAF1
SCHEMBL7114570 0.75 PTGS2 (0.47) PTGS2FAAHAPAF1GRM7POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0348793-B1 PROCESS FOR THE PREPARATION OF KETONES BASF Aktiengesellschaft (DE) 1993-09-22 EP disclosed
EP-0348793-A2 Process for the preparation of ketones BASF Aktiengesellschaft (DE) 1990-01-03 EP disclosed