SCHEMBL9508865

SCHEMBL9508865

O=S(=O)(Cl)c1ccc2c(c1)Sc1cc(S(=O)(=O)Cl)ccc1O2

nearest known ligand 0.39

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.35
HSD17B10 Q99714 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
AHR P35869 1/20 0.30
NOX1 Q9Y5S8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7351588 0.92 ALDH1A1 (0.38) ALDH1A1HSD17B10TDP1AHR
SCHEMBL9511439 0.79 ALDH1A1 (0.41) ALDH1A1HSD17B10TDP1NOX1
SCHEMBL9507650 0.79 ALDH1A1 (0.41) ALDH1A1HSD17B10TDP1NOX1
SCHEMBL7357401 0.74 TDP1 (0.46) ALDH1A1HSD17B10TDP1NOX1
SCHEMBL28774202 0.68 ALDH1A1 (0.38) ALDH1A1HSD17B10TDP1
SCHEMBL30204094 0.68 ALDH1A1 (0.38) ALDH1A1HSD17B10TDP1
SCHEMBL3534174 0.68 KIF11 (0.45) ALDH1A1HSD17B10TDP1
SCHEMBL7358246 0.67 MAOA (0.55) ALDH1A1HSD17B10TDP1
SCHEMBL29437166 0.67 CA12 (0.54) ALDH1A1HSD17B10TDP1
SCHEMBL560493 0.67 CA12 (0.54) ALDH1A1HSD17B10TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0399293-B1 PROCESS FOR PREPARING 2-CHLORO-4-NITRO-ALKYLBENZENE BAYER AG (DE) 1993-09-01 EP disclosed
US-5095157-A Friedel-crafts catalyst BAYER AKTIENGESELLSCHAFT (DE) 1992-03-10 US disclosed
EP-0399293-A1 Process for preparing 2-chloro-4-nitro-alkylbenzene BAYER AG (DE) 1990-11-28 EP disclosed