SCHEMBL9507650

SCHEMBL9507650

O=S(=O)(Cl)c1ccc2c(c1)Sc1ccc(S(=O)(=O)Cl)cc1S2

nearest known ligand 0.41

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.41
HSD17B10 Q99714 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
NOX1 Q9Y5S8 1/20 0.36
CYP3A4 P08684 1/20 0.31
MAPK1 P28482 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9511439 1.00 ALDH1A1 (0.41) ALDH1A1HSD17B10TDP1NOX1CYP3A4
SCHEMBL7357401 0.94 TDP1 (0.46) ALDH1A1HSD17B10TDP1NOX1CYP3A4
SCHEMBL9508865 0.79 ALDH1A1 (0.35) ALDH1A1HSD17B10TDP1NOX1
SCHEMBL9508137 0.77 ALDH1A1 (0.45) ALDH1A1HSD17B10TDP1
SCHEMBL7351588 0.73 ALDH1A1 (0.38) ALDH1A1HSD17B10TDP1
SCHEMBL7360175 0.72 TSHR (0.46) ALDH1A1HSD17B10TDP1CYP3A4
SCHEMBL9508903 0.71 HTR6 (0.54) ALDH1A1NOX1
SCHEMBL651902 0.71 ALDH1A1 (0.71) ALDH1A1HSD17B10TDP1CYP3A4MAPK1
SCHEMBL30357699 0.70 LMNA (0.48) ALDH1A1HSD17B10TDP1
SCHEMBL2263563 0.70 LMNA (0.48) ALDH1A1HSD17B10TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0399293-B1 PROCESS FOR PREPARING 2-CHLORO-4-NITRO-ALKYLBENZENE BAYER AG (DE) 1993-09-01 EP disclosed
US-5095157-A Friedel-crafts catalyst BAYER AKTIENGESELLSCHAFT (DE) 1992-03-10 US disclosed
EP-0399293-A1 Process for preparing 2-chloro-4-nitro-alkylbenzene BAYER AG (DE) 1990-11-28 EP disclosed