Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 3/20 | 0.50 |
| ▸ | PPARA | Q07869 | 3/20 | 0.50 |
| ▸ | LPL | P06858 | 2/20 | 0.50 |
| ▸ | LIPG | Q9Y5X9 | 2/20 | 0.50 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.50 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.50 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.47 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.47 |
| ▸ | THRA | P10827 | 2/20 | 0.46 |
| ▸ | THRB | P10828 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9507514 | 1.00 | PPARG (0.50) | PPARGPPARALPLLIPGSPHK2 | |
| SCHEMBL9506855 | 1.00 | PPARG (0.50) | PPARGPPARALPLLIPGSPHK2 | |
| SCHEMBL9504753 | 1.00 | PPARG (0.50) | PPARGPPARALPLLIPGSPHK2 | |
| SCHEMBL9508797 | 1.00 | PPARG (0.50) | PPARGPPARALPLLIPGSPHK2 | |
| SCHEMBL27671417 | 1.00 | PPARG (0.50) | PPARGPPARALPLLIPGSPHK2 | |
| SCHEMBL9507490 | 1.00 | PPARG (0.50) | PPARGPPARALPLLIPGSPHK2 | |
| SCHEMBL9508836 | 1.00 | PPARG (0.50) | PPARGPPARALPLLIPGSPHK2 | |
| SCHEMBL9508299 | 0.88 | ALOX5 (0.58) | PPARGCYP4F2CYP4A11 | |
| SCHEMBL9016911 | 0.85 | ALDH1A1 (0.55) | PPARGPPARALPLLIPGSPHK2 | |
| SCHEMBL9504722 | 0.83 | PPARA (0.52) | PPARGPPARALPLLIPGSPHK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0161939-B1 | ARYLHYDROXAMATES | E.R. Squibb & Sons, Inc. (US) | 1993-07-21 | — | — | EP | disclosed |
| CN-1012500-B | Process for preparing aryl hydroxamates | SQUIBB & SONS INC (US) | 1991-05-01 | — | — | CN | disclosed |
| CN-85104470-A | The method for preparing arythydroxamtes | — | 1986-10-01 | — | — | CN | disclosed |
| US-4607053-A | L2POXYGENASE INHIBITORS | E. R. SQUIBB & SONS, INC. (US) | 1986-08-19 | — | — | US | disclosed |
| EP-0161939-A2 | Arylhydroxamates | E.R. Squibb & Sons, Inc. (US) | 1985-11-21 | — | — | EP | disclosed |