SCHEMBL9508911

SCHEMBL9508911

C=C/C(=C(\C#N)C(=O)O)c1ccc(/C(C=C)=C(/C#N)C(=O)O)cc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AKT1 P31749 1/20 0.38
ALDH5A1 P51649 1/20 0.36
ABAT P80404 1/20 0.36
ALDH1A1 P00352 3/20 0.36
MAPT P10636 2/20 0.36
MAPK1 P28482 2/20 0.36
LMNA P02545 1/20 0.36
XBP1 P17861 1/20 0.36
RAB9A P51151 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36
EGFR P00533 3/20 0.34
KDM4E B2RXH2 2/20 0.34
CYP3A4 P08684 2/20 0.34
HPGD P15428 2/20 0.34
CISD1 Q9NZ45 1/20 0.34
SLC16A3 O15427 1/20 0.34
SLC16A1 P53985 1/20 0.34
GPR35 Q9HC97 1/20 0.34
TDP1 Q9NUW8 3/20 0.33
POLB P06746 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9362180 0.92 AKT1 (0.48) AKT1ALDH1A1MAPTMAPK1LMNA
SCHEMBL10938243 0.88 AKT1 (0.40) AKT1ALDH1A1MAPTMAPK1LMNA
SCHEMBL19117004 0.77 ALDH1A1 (0.42) AKT1ALDH1A1MAPTMAPK1LMNA
SCHEMBL9362014 0.75 ALDH1A1 (0.41) AKT1ALDH1A1MAPTMAPK1LMNA
SCHEMBL15988463 0.71 CPT1B (0.47) ALDH5A1ABATALDH1A1MAPTLMNA
SCHEMBL2875196 0.70 LMNA (0.35) LMNA
SCHEMBL2875198 0.70 LMNA (0.35) LMNA
SCHEMBL11061361 0.68 ALDH1A1 (0.38) ALDH1A1LMNATDP1
SCHEMBL22197166 0.68 CYP1A2 (0.49) ALDH1A1MAPTMAPK1LMNAXBP1
SCHEMBL14167929 0.68 CPT1B (0.48) ALDH1A1MAPTLMNAKDM4ECYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-58099457-A None JP disclosed
JP-59155417-A None JP disclosed
JP-1213321-A None JP disclosed
EP-0205083-B1 IMAGE FORMING METHOD AND TRANSFER RECORDING MEDIUM THEREFOR CANON KABUSHIKI KAISHA (JP) 1993-09-01 EP disclosed
US-5015552-A Multilayer optical image recording process involving crosslinking, treatment with heat or light, transferring CANON KABUSHIKI KAISHA (JP) 1991-05-14 US disclosed
US-5005028-A Image forming method and transfer recording medium therefor CANON KABUSHIKI KAISHA (JP) 1991-04-02 US disclosed
JP-H01213321-A PRODUCTION OF NOVEL THIN FILM POLYMER AGENCY OF IND SCIENCE & TECHNOL 1989-08-28 JP disclosed
EP-0205083-A2 Image forming method and transfer recording medium therefor CANON KABUSHIKI KAISHA (JP) 1986-12-17 EP disclosed
US-4495343-A Visible light-sensitive polyester polymer and visible light-sensitive resin composition containing said polymer TEIJIN LIMITED (JP) 1985-01-22 US disclosed
US-4495343-A Visible light-sensitive polyester polymer and visible light-sensitive resin composition containing said polymer TEIJIN LIMITED (JP) 1985-01-22 US disclosed
JP-S59155417-A HEIGHTENING OF SENSITIVITY OF VISIBLELIGHT-SENSITIVE RESIN AND COMPOSITION OF SAID RESIN OF HEIGHTENED SENSITIVITY TEIJIN LTD 1984-09-04 JP disclosed
JP-S5899457-A PHENYLENEBIS(ALPHA-CYANOBUTADIENECARBOXYLIC ACID) OR ITS DERIVATIVE AND ITS PREPARATION TEIJIN LTD 1983-06-13 JP disclosed