Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2875196 | 1.00 | LMNA (0.35) | LMNA | |
| SCHEMBL11061361 | 0.74 | ALDH1A1 (0.38) | LMNA | |
| SCHEMBL17109663 | 0.73 | ALDH1A1 (0.38) | — | |
| SCHEMBL7195077 | 0.73 | ALDH1A1 (0.32) | LMNA | |
| SCHEMBL7195083 | 0.73 | ALDH1A1 (0.32) | LMNA | |
| SCHEMBL9171301 | 0.70 | ALDH1A1 (0.38) | — | |
| SCHEMBL7911515 | 0.70 | — | — | |
| SCHEMBL9508911 | 0.70 | AKT1 (0.38) | LMNA | |
| SCHEMBL16027145 | 0.68 | — | — | |
| SCHEMBL6293725 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10927071-B2 | Process for preparing electron deficient olefins | Henkel IP & Holding GmbH (DE) | 2021-02-23 | — | — | US | claimed |
| EP-3558934-A1 | PROCESS FOR PREPARING ELECTRON DEFICIENT OLEFINS | Henkel IP & Holding GmbH (DE) | 2019-10-30 | — | — | EP | claimed |
| US-20190292141-A1 | PROCESS FOR PREPARING ELECTRON DEFICIENT OLEFINS | HENKEL AG & CO. KGAA (DE) | 2019-09-26 | — | — | US | claimed |
| WO-2018114458-A1 | PROCESS FOR PREPARING ELECTRON DEFICIENT OLEFINS | Henkel IP & Holding GmbH (DE) | 2018-06-28 | — | — | WO | claimed |
| US-7718821-B1 | Method of preparing electron deficient olefins | LOCTITE (R&D) LIMITED (IL) | 2010-05-18 | — | — | US | claimed |
| US-7659423-B1 | Method of preparing electron deficient olefins in polar solvents | LOCTITE (R&D) LIMITED (IE) | 2010-02-09 | — | — | US | claimed |
| US-7569719-B1 | Method of preparing electron deficient olefins | LOCTITE (R&D) LIMITED (IE) | 2009-08-04 | — | — | US | claimed |
| EP-3558934-B1 | PROCESS FOR PREPARING ELECTRON DEFICIENT OLEFINS | HENKEL AG & CO KGAA (DE) | 2025-04-30 | — | — | EP | disclosed |
| US-10927071-B2 | Process for preparing electron deficient olefins | Henkel IP & Holding GmbH (DE) | 2021-02-23 | — | — | US | disclosed |
| EP-3558934-A1 | PROCESS FOR PREPARING ELECTRON DEFICIENT OLEFINS | Henkel IP & Holding GmbH (DE) | 2019-10-30 | — | — | EP | disclosed |
| US-20190292141-A1 | PROCESS FOR PREPARING ELECTRON DEFICIENT OLEFINS | HENKEL AG & CO. KGAA (DE) | 2019-09-26 | — | — | US | disclosed |
| WO-2018114458-A1 | PROCESS FOR PREPARING ELECTRON DEFICIENT OLEFINS | Henkel IP & Holding GmbH (DE) | 2018-06-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190292141-A1 | PROCESS FOR PREPARING ELECTRON DEFICIENT OLEFINS | PCCA, COASY, LIG4 | LMNA 2757/4885 |
| US-10927071-B2 | Process for preparing electron deficient olefins | PCCA, COASY, LIG4 | LMNA 2757/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.