Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 1/20 | 0.54 |
| ▸ | DRD2 | P14416 | 3/20 | 0.50 |
| ▸ | DRD1 | P21728 | 2/20 | 0.50 |
| ▸ | DRD3 | P35462 | 2/20 | 0.50 |
| ▸ | DRD4 | P21917 | 1/20 | 0.50 |
| ▸ | DRD5 | P21918 | 1/20 | 0.50 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.50 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.50 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.50 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1551880 | 0.84 | MEN1 (0.41) | ENPP2TAAR1CYP1A2KMT2A | |
| SCHEMBL2809012 | 0.83 | ENPP2 (0.50) | ENPP2DRD2DRD1DRD3DRD4 | |
| SCHEMBL19609051 | 0.82 | ENPP2 (0.58) | ENPP2DRD2DRD1DRD3DRD4 | |
| SCHEMBL7773782 | 0.78 | MIF (0.55) | ENPP2DRD2DRD1DRD3DRD4 | |
| SCHEMBL357440 | 0.78 | ENPP2 (0.54) | ENPP2DRD2DRD1DRD3DRD4 | |
| SCHEMBL909770 | 0.78 | DRD2 (0.55) | ENPP2DRD2DRD1DRD3DRD4 | |
| SCHEMBL1233598 | 0.78 | MMP3 (0.65) | ENPP2DRD2DRD1DRD3DRD4 | |
| SCHEMBL17847703 | 0.75 | ENPP2 (0.60) | ENPP2DRD2DRD1DRD3DRD4 | |
| SCHEMBL29462919 | 0.75 | — | — | |
| SCHEMBL51757 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0295126-B1 | ARYLAMINE-CONTAINING POLYHYDROXY ETHER RESINS | XEROX CORPORATION (US) | 1993-08-04 | — | — | EP | disclosed |
| US-4818650-A | Arylamine containing polyhydroxy ether resins and system utilizing arylamine containing polyhydroxyl ether resins | XEROX CORPORATION (US) | 1989-04-04 | — | — | US | disclosed |
| EP-0295126-A2 | Arylamine-containing polyhydroxy ether resins | XEROX CORPORATION (US) | 1988-12-14 | — | — | EP | disclosed |